2-Benzyl-2-dimethylamino-1-(4-morpholinophenyl)-1-butanone

Base Information

• Chemical Name: 2-Benzyl-2-dimethylamino-1-(4-morpholinophenyl)-1-butanone
• CAS No.: 119313-12-1
• Deprecated CAS: 136797-29-0,748160-22-7,1392498-45-1,1393715-98-4,2102600-95-1,2253103-97-6,1392498-45-1,748160-22-7
• Molecular Formula: C23H30N2O2
• Molecular Weight: 366.503
• Hs Code.: 29349990
• European Community (EC) Number: 404-360-3,601-598-1
• UNII: 413O6RKS6B
• DSSTox Substance ID: DTXSID5044786
• Nikkaji Number: J261.950D
• Wikidata: Q27258386
• ChEMBL ID: CHEMBL3187611
• Mol file: 119313-12-1.mol

Synonyms:119313-12-1;2-Benzyl-2-dimethylamino-1-(4-morpholinophenyl)-1-butanone;2-Benzyl-2-(dimethylamino)-4'-morpholinobutyrophenone;Irgacure 369;2-benzyl-2-(dimethylamino)-1-(4-morpholinophenyl)butan-1-one;DTXSID5044786;2-benzyl-2-(dimethylamino)-1-(4-morpholin-4-ylphenyl)butan-1-one;UNII-413O6RKS6B;413O6RKS6B;2-Benzyl-2-(dimethylamino)-1-(4-(morpholin-4-yl)phenyl)butan-1-one;2-Benzyl-2-(dimethylamino)-1-[4-(4-morpholinyl)phenyl]-1-butanone;2-Benzyl-2-dimethylamino-4'-morpholinobutyrophenone;1-Butanone, 2-(dimethylamino)-1-[4-(4-morpholinyl)phenyl]-2-(phenylmethyl)-;1-Butanone, 2-(dimethylamino)-1-(4-(4-morpholinyl)phenyl)-2-(phenylmethyl)-;EC 404-360-3;2-benzyl-2-n,n-dimethylamino-1-(4-morpholinophenyl)-1-butanone;2-Benzyl-2-(dimethylamino)-1-[4-(morpholin-4-yl)phenyl]butan-1-one;photoinitiator369;Photocure 3665;Ciba 369;IRGACURE369;PHOTOINITIATOR 369;Irg 369;SCHEMBL35868;CHEMBL3187611;DTXCID3024786;CGI 369;Tox21_301707;IC 369;MFCD00191775;AKOS015901469;CS-W009775;NCGC00256142-01;DS-12208;LS-46712;J261.950D;B3914;CAS-119313-12-1;FT-0712767;I 369;O10663;Q27258386;2-benzyl-2-dimethylamino-1-(4-morpholinophenyl)butanone;2-benzyl-2-dimethylamino-1 -(4morpholinophenyl)butan-1-one;2-benzyl-2-dimethylamino-1-(4-morpholinophenyl)-butanone-1;2-benzyl-2-dimethylamino-1-(4-morpholinophenyl)butan-1-one;2-benzyl-2-(dimethylamino)-1-(4-morpholinophenyl)-1-butanone;2-Benzyl-2-(dimethylamino)-1-(4-morpholinophenyl)butanone-1;2-Benzyl-2-(dimethylamino)-4'-morpholinobutyrophenone, 97%;2-benzyl-2-dimethylamino-1-(4-morpholinophenyl) -1-butanone;2-Benzyl-2-dimethylamino-1-(4-morpholinophenyl)-butan-1-one;2-Benzyl-2-(dimethylamino)-1-[4-(morpholino)phenyl]-1-butanone;2-Benzyl-2-N N-dimethylamino-1-(4-morpholinophenyl)-1-butanone;.ALPHA.-BENZYL-.ALPHA.-(DIMETHYLAMINO)-4-MORPHOLINOBUTYROPHENONE;1-butanona, 2-(dimetilamino)-1-[4-(4-morfolinil)fenil]-2-(fenilmetil)-;2-(DIMETHYLAMINO)-1-(4-MORPHOLINOPHENYL)-2-BENZYL-1-BUTANONE;2-(Dimethylamino)-1-[4-(4-morpholinyl)phenyl]-2-(phenylmethyl)-1-butanone;2-benzyl-2-(dimethylamino)-1-(4-(4-morpholinyl) phenyl)-1-butanone;Irgacure 369 (2-Benzyl-2-(dimethylamino)-1-[4-(morpholinyl) phenyl)]-1-butanone)

Chemical Property of 2-Benzyl-2-dimethylamino-1-(4-morpholinophenyl)-1-butanone

Chemical Property:

• Vapor Pressure: 0-0.01Pa at 25-95℃
• Melting Point: 116-119 °C(lit.)
• Boiling Point: 528.8 °C at 760 mmHg
• PKA: 7.04±0.50(Predicted)
• Flash Point: 273.6 °C
• PSA: 32.78000
• Density: 1.094 g/cm³
• LogP: 3.72400
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: 3240 in mg/100g standard fat at 20 ℃
• Water Solubility.: 5.9mg/L at 20℃
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 7
• Exact Mass: 366.230728204
• Heavy Atom Count: 27
• Complexity: 461

Purity/Quality:

99%MIN ^*data from raw suppliers

2-Benzyl-2-(dimethylamino)-4'-morpholinobutyrophenone >98.0%(HPLC)(T) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): N
• Hazard Codes: N
• Statements: 50/53
• Safety Statements: 60-61

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCC(CC1=CC=CC=C1)(C(=O)C2=CC=C(C=C2)N3CCOCC3)N(C)C
• Uses: DBMP can be used as a dopant to dope silicone elastomer for the formation of 3D biocompatible scaffolds. It can also be used in two photon polymerization for the micro-fabrication of 3D hydrogels for potential biomedical and tissue engineering applications. UV solidify ink and coating

Technology Process of 2-Benzyl-2-dimethylamino-1-(4-morpholinophenyl)-1-butanone

There total 17 articles about 2-Benzyl-2-dimethylamino-1-(4-morpholinophenyl)-1-butanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

morpholine (110-91-8,99108-56-2) + 2-benzyl-2-(dimethylamino)-1-(4-fluorophenyl)-butan-1-one (119312-61-7) → 2-benzyl-2-(dimethylamino)-1-(4-morpholinophenyl)-butan 1-one (119313-12-1)

Guidance literature:

In 1,2-dichloro-ethane; Solvent; Reflux;

Reference yield: 76.0%

morpholine (110-91-8,99108-56-2) + 2-benzyl-1-(4-chlorophenyl)-2-(dimethylamino)-butan-1-one → 2-benzyl-2-(dimethylamino)-1-(4-morpholinophenyl)-butan 1-one (119313-12-1)

Guidance literature:

With ethylenediaminetetraacetic acid; copper; at 180 ℃; for 20h; under 8250.83 Torr;

Reference yield:

C23H31N2O2(1+)*Cl(1-) → 2-benzyl-2-(dimethylamino)-1-(4-morpholinophenyl)-butan 1-one (119313-12-1)

Guidance literature:

With potassium carbonate; at 20 - 40 ℃; for 4h; Reagent/catalyst; Temperature;

upstream raw materials:

morpholine

2-benzyl-2-(dimethylamino)-1-(4-fluorophenyl)-butan-1-one

potassium carbonate

fluorobenzene

Downstream raw materials:

4-morpholinobenzoyl radical

1-phenyl-2-(dimethylamino)but-2-yl radical

Refernces

• 1、 -. "Synthetic method of 2-benzyl-2-dimethylamino-1-(4-morpholinophenyl) butanone". . . Retrieved 2018/09/08.
• 2、 -. "Oxygen-containing titanocenes, and the use thereof". . . Retrieved 2008/06/13.