3-BROMO-5-NITROBENZALDEHYDE

Base Information

• Chemical Name: 3-BROMO-5-NITROBENZALDEHYDE
• CAS No.: 355134-13-3
• Molecular Formula: C7H4BrNO3
• Molecular Weight: 230.018
• Hs Code.: 2913000090
• Mol file: 355134-13-3.mol

Synonyms:3-BROMO-5-NITROBENZALDEHYDE;3-Fluoro-5-nitrobenzaldehyde;3-BroMo-5-nitrobenzaldehyde, 97+%;3-Bromo-5-formylnitrobenzene

Chemical Property of 3-BROMO-5-NITROBENZALDEHYDE

Chemical Property:

• Melting Point: 101-106 °C
• Boiling Point: 306.9 °C at 760 mmHg
• Flash Point: 139.4 °C
• PSA: 62.89000
• Density: 1.781 g/cm³
• LogP: 2.69300
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Solubility.: soluble in Methanol

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-Bromo-5-nitrobenzaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22-36/37/38-43
• Safety Statements: 26-36/37

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of 3-BROMO-5-NITROBENZALDEHYDE

There total 3 articles about 3-BROMO-5-NITROBENZALDEHYDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

3-nitro-benzaldehyde (99-61-6) → 3-bromo-5-nitrobenzaldehyde (355134-13-3)

Guidance literature:

With N-Bromosuccinimide; sulfuric acid; at 60 ℃; for 2h;

DOI:10.1021/acs.jmedchem.8b00076

Reference yield: 88.0%

(3-bromo-5-nitrophenyl)methanol (139194-79-9) → 3-bromo-5-nitrobenzaldehyde (355134-13-3)

Guidance literature:

With oxygen; caesium carbonate; In water; for 2h; Reflux;

DOI:10.1016/j.catcom.2014.01.030

Reference yield:

→ 3-bromo-5-nitrobenzaldehyde (355134-13-3)

Guidance literature:

With ethanol;

upstream raw materials:

3-nitro-benzaldehyde

(3-bromo-5-nitrophenyl)methanol

Downstream raw materials:

2-(3-bromo-5-nitrophenyl)-1,3-dioxolane

Refernces

• 1、 Grimster, Neil P.,Anderson, Erica,Alimzhanov, Marat,Bebernitz, Geraldine,Bell, Kirsten,Chuaqui, Claudio,Deegan, Tracy,Ferguson, Andrew D.,Gero, Thomas,Harsch, Andreas,Huszar, Dennis,Kawatkar, Aarti,Kettle, Jason G.,Lyne, Paul,Read, Jon A.,Rivard Costa, Caroline,Ruston, Linette,Schroeder, Patricia,Shi, Jie,Su, Qibin,Throner, Scott,Toader, Dorin,Vasbinder, Melissa,Woessner, Richard,Wang, Haixia,Wu, Allan,Ye, Minwei,Zheng, Weijia,Zinda, Michael. "Discovery and Optimization of a Novel Series of Highly Selective JAK1 Kinase Inhibitors". supporting information. p. 5235 - 5244. Retrieved 2018/06/11.
• 2、 Albadi, Jalal,Alihoseinzadeh, Amir,Razeghi, Abdolhosein. "Novel metal oxide nanocomposite of Au/CuO-ZnO for recyclable catalytic aerobic oxidation of alcohols in water". . p. 1 - 5. Retrieved 2014/03/21.