Bis(di-tert-butyl)-4-dimethylaminophenylphosphine

Base Information

• Chemical Name: Bis(di-tert-butyl)-4-dimethylaminophenylphosphine
• CAS No.: 932710-63-9
• Molecular Formula: C16H28NP
• Molecular Weight: 265.379
• Hs Code.: 2921420090
• Mol file: 932710-63-9.mol

Synonyms:Bis(di-tert-butyl)-4-dimethylaminophenylphosphine;[(4-Dimethylaminophenyl)]di(tert-butyl)phosphine;[4-(Dimethylamino)phenyl]bis(tert-butyl)phosphine;N,N-Dimethyl 4-(di(tert-butyl)phosphino)aniline;95% A-taPhos;(4-(N,N-DiMethylaMino)phenyl)di-tert-butyl phosphine,95% A-taPhos;(4-(N,N-DiMethylaMino)phenyl)di-tert-butyl phosphine,95%;[4-(N,N-DiMethylaMino)phenyl]di-t-butylphosphine, Min. 95% aMphos

Chemical Property of Bis(di-tert-butyl)-4-dimethylaminophenylphosphine

Chemical Property:

• Melting Point: 57-61°C
• Boiling Point: 349.1±25.0 °C(Predicted)
• PKA: 4.73±0.24(Predicted)
• PSA: 16.83000
• LogP: 4.45680
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility.: soluble in Acetone

Purity/Quality:

98% ^*data from raw suppliers

Amphos ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/38
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Amphos can be used as an electrophotographic photoreceptor, process cartridge, and image forming electrode. Ligand used to prepare a palladium dichloride catalyst (678740) on treatment with PdCl2(COD). The catalyst effectively cross-couples aryl boronic acids with heteroaryl chlorides.

Technology Process of Bis(di-tert-butyl)-4-dimethylaminophenylphosphine

There total 9 articles about Bis(di-tert-butyl)-4-dimethylaminophenylphosphine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

di-tert-butylphosphonium chloride + N,N-dimethyl-aniline (121-69-7,77733-26-7) → (4-(N,N-dimethylamino)phenyl)-di-tert-butylphosphine (932710-63-9)

Guidance literature:

With dmap; copper (I) acetate; In toluene; at 120 ℃; for 8h; Temperature; Inert atmosphere;

Reference yield: 85.0%

di(tert-butyl)chlorophosphine (13716-10-4) + 4-N,N-dimethylaminophenyl magnesium chloride (108949-55-9) → (4-(N,N-dimethylamino)phenyl)-di-tert-butylphosphine (932710-63-9)

Guidance literature:

di(tert-butyl)chlorophosphine; 4-N,N-dimethylaminophenyl magnesium chloride; at -30 ℃; for 0.166667h; Inert atmosphere;

With ammonium chloride; In water; at -30 ℃; for 0.5h;

Reference yield: 85.0%

di(tert-butyl)chlorophosphine (13716-10-4) + 4-dimethylaminophenylmagnesium bromide (7353-91-5) → (4-(N,N-dimethylamino)phenyl)-di-tert-butylphosphine (932710-63-9)

Guidance literature:

di(tert-butyl)chlorophosphine; 4-dimethylaminophenylmagnesium bromide; at -60 ℃; for 0.133333h; Inert atmosphere;

With ammonium chloride; In water; at -60 ℃; for 0.5h;

upstream raw materials:

di-tert-butylphosphine

4-bromo-N,N-dimethylaniline

N,N-dimethyl-aniline

di(tert-butyl)chlorophosphine

Downstream raw materials:

bis(di-tert-?butyl(4-?dimethylaminophenyl)?phosphine)?dichloropalladium(II)

[4-(di-tert-butylphosphino)-N,N-dimethylaniline-2-(2’-aminobiphenyl)]palladium(II) methanesulfonate

Refernces

• 1、 -. "Di-tert-butyl - 4 - dimethyl amino phosphonate and double (di-tert-butyl - 4 - dimethyl amino phosphonate) preparation method of catalysts". Paragraph 0061-0063. . Retrieved 2017/08/25.
• 2、 -. "NOVEL CATALYSTS". Page/Page column 71. . Retrieved 2012/06/01.