4-NITROPHENYL-BETA-D-CELLOBIOSIDE

Base Information

• Chemical Name: 4-NITROPHENYL-BETA-D-CELLOBIOSIDE
• CAS No.: 3482-57-3
• Molecular Formula: C18H25NO13
• Molecular Weight: 463.395
• Hs Code.: 29400090
• Mol file: 3482-57-3.mol

Synonyms:Cellobioside,p-nitrophenyl (7CI);Cellobioside, p-nitrophenyl, b-D- (8CI);p-Nitrophenyl cellobioside;p-Nitrophenyl b-D-cellobioside;p-Nitrophenyl b-cellobioside;

Chemical Property of 4-NITROPHENYL-BETA-D-CELLOBIOSIDE

Chemical Property:

• Appearance/Colour: Off-White Powder
• Vapor Pressure: 1.07E-26mmHg at 25°C
• Melting Point: 249-250ºC
• Refractive Index: 1.67
• Boiling Point: 795.6 ºC at 760 mmHg
• PKA: 12.43±0.70(Predicted)
• Flash Point: 435 ºC
• PSA: 224.35000
• Density: 1.7 g/cm³
• LogP: -2.87910
• Storage Temp.: 2-8°C
• Solubility.: methanol: water (2:3): 50 mg/mL, clear, faintly yellow

Purity/Quality:

98%, ^*data from raw suppliers

p-Nitrophenyl b-D-Cellobioside ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: p-Nitrophenyl β-D-Cellobioside (cas# 3482-57-3) is a compound useful in organic synthesis.

Technology Process of 4-NITROPHENYL-BETA-D-CELLOBIOSIDE

There total 51 articles about 4-NITROPHENYL-BETA-D-CELLOBIOSIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

p-nitrophenyl 2,3,6-tri-O-acetyl-4-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-β-D-glucopyranoside (69948-03-4) → p-nitrophenyl β-D-cellobioside (3482-57-3)

Guidance literature:

With sodium methylate; In methanol; Ambient temperature;

DOI:10.1016/S0008-6215(98)00294-8

Reference yield: 90.0%

C32H39NO20 → p-nitrophenyl-β-D-glucopyranosyl-(1→4)-O-α-D-glucopyranoside (3482-57-3,4419-94-7,7344-00-5,17400-77-0,56846-39-0,78248-67-6,80446-81-7)

Guidance literature:

With sodium methylate; In methanol; at 0 - 20 ℃; for 3h;

Reference yield: 23.0%

β‐cyclodextrin (7585-39-9) + 4-nitrophenyl-β-D-glucoside (2492-87-7) → p-nitrophenyl-β-D-glucopyranosyl-(1→4)-O-α-D-glucopyranoside (3482-57-3,4419-94-7,7344-00-5,17400-77-0,56846-39-0,78248-67-6,80446-81-7) + p-nitrophenyl-β-D-glucopyranosyl-(1→6)-O-α-D-glucopyranoside (335193-88-9) + p-nitrophenyl-β-D-glucopyranosyl-(1→3)-O-α-D-glucopyranoside

Guidance literature:

With cyclodextrin glycosyltransferase from Bacillus macerans; In aq. phosphate buffer; at 40 ℃; for 148h; pH=7; Reagent/catalyst; Temperature; Enzymatic reaction;

DOI:10.1016/j.carres.2014.11.010

upstream raw materials:

1-deoxy-1-fluoro-α-D-glucose

4-nitrophenyl-β-D-glucoside

p-nitrophenyl 2,3,6-tri-O-acetyl-4-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-β-D-glucopyranoside

4-nitrophenyl β-D-glucopyranosyl-(1→4)-β-D-glucopyranosyl-(1→4)-β-D-glucopyranoside

Downstream raw materials:

p-aminophenyl β-cellobioside

(4-amino-phenyl)-(O⁴-α-D-glucopyranosyl-β-D-glucopyranoside)

4-nitro-phenol

4-nitrophenyl-α-D-glucopyranoside

Refernces

• 1、 -. "SYNTHETIC CATALYSTS FOR CARBOHYDRATE PROCESSING". . . Retrieved 2022/01/24.
• 2、 Pozzo, Tania,Plaza, Merichel,Romero-Garcia, Javier,Faijes, Magda,Karlsson, Eva Nordberg,Planas, Antoni. "Glycosynthases from Thermotoga neapolitana β-glucosidase 1A: A comparison of α-glucosyl fluoride and in situ-generated α-glycosyl formate donors". . p. 132 - 139. Retrieved 2014/07/21.