Dienogest

Base Information Edit

Chemical Name:Dienogest
CAS No.:65928-58-7
Molecular Formula:C₂₀H₂₅NO₂
Molecular Weight:311.424
Hs Code.:
European Community (EC) Number:639-448-2
UNII:46M3EV8HHE
DSSTox Substance ID:DTXSID80891478
Nikkaji Number:J23.763I
Wikipedia:Dienogest
Wikidata:Q139160
NCI Thesaurus Code:C87238
RXCUI:22968
Pharos Ligand ID:Y5MTLGFFNJ13
Metabolomics Workbench ID:65208
ChEMBL ID:CHEMBL1201864
Mol file:65928-58-7.mol

Synonyms:17 alpha-cyanomethyl-17 beta-hydroxy-13 beta-methylgona-4,9-dien-3-one;17 alpha-cyanomethyl-17 beta-hydroxyestra-4,9(10)-diene-3-one;19-norpregna-4,9-diene-21-nitrile, 17-hydroxy-3-oxo-, (17alpha)-;dienogest;STS 557;STS-557

Suppliers and Price of Dienogest

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Dienogest
25mg
$ 275.00

TRC
Dienogest
1g
$ 1005.00

TCI Chemical
Dienogest >98.0%(HPLC)
250mg
$ 746.00

TCI Chemical
Dienogest >98.0%(HPLC)
50mg
$ 214.00

Labseeker
Dienogestrel 95
10g
$ 385.00

DC Chemicals
Dienogest >98%
100 mg
$ 300.00

DC Chemicals
Dienogest >98%
1 g
$ 1200.00

Crysdot
Dienogest 98+%
10mg
$ 59.00

Crysdot
Dienogest 98+%
5mg
$ 49.00

Crysdot
Dienogest 98+%
50mg
$ 188.00

Total 184 raw suppliers

Chemical Property of Dienogest Edit

Chemical Property:

Appearance/Colour:Pale yellow solid
Vapor Pressure:2.42E-14mmHg at 25°C
Melting Point:210-214 °C
Refractive Index:1.589
Boiling Point:549 °C at 760 mmHg
PKA:13?+-.0.40(Predicted)
Flash Point:285.8 °C
PSA：61.09000
Density:1.2 g/cm³
LogP:3.83718
Storage Temp.:-20°C Freezer
Solubility.:Chloroform (Slightly), Pyridine (Slightly)
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:311.188529040
Heavy Atom Count:23
Complexity:679

Purity/Quality:

99%min ^*data from raw suppliers

Dienogest ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC12CCC3=C4CCC(=O)C=C4CCC3C1CCC2(CC#N)O
Isomeric SMILES:C[C@]12CCC3=C4CCC(=O)C=C4CC[C@H]3[C@@H]1CC[C@]2(CC#N)O
Recent ClinicalTrials:A Study to Learn More About How Safe Dienogest is and How Well it Works Under Real World Conditions in Indian Women With Endometriosis
Recent EU Clinical Trials:Assisted reproductive technology (ART) and pregnancy outcomes in women with adenomyosis (internal endometriosis) according to stimulation protocol in relation to immunological and endometrial features: a prospective, randomized study.
Recent NIPH Clinical Trials:The efficacy and safety of long-term low-dose Dienogest in patients with dysmenorrhea due to endometriosis.
Description Dienoest is a selective progesterone drug that has been launched in recent years. It can stabilize endometrial tissue by specifically binding to ethylene nortestosterone and progesterone derivatives. Studies have found that tumor necrosis factor (TNF) and interleukin (IL-8) tend to increase in patients with endometriosis.
Physical properties Dienogestrel is a pale yellow solid.
Uses Dienogest is an orally active synthetic progesterone (or progestin). It is available for use as an oral contraceptive in combination with ethinylestradiol. It has antiandrogenic activity and as a result can improve androgenic symptoms. Derivative of 19-Nortestosterone. In combination with estrogen as oral contraceptive. Progestogen.

Technology Process of Dienogest

There total 18 articles about Dienogest which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.6%