3-Dimethylamino-2-methylpropyl chloride hydrochloride

Base Information

• Chemical Name: 3-Dimethylamino-2-methylpropyl chloride hydrochloride
• CAS No.: 4261-67-0
• Molecular Formula: C6H14ClN.ClH
• Molecular Weight: 172.098
• Hs Code.: 29211999
• European Community (EC) Number: 224-237-6
• DSSTox Substance ID: DTXSID60962610
• Mol file: 4261-67-0.mol

Synonyms:4261-67-0;3-Dimethylamino-2-methylpropyl chloride hydrochloride;3-chloro-N,N,2-trimethylpropan-1-amine hydrochloride;3-chloro-N,N,2-trimethylpropan-1-amine;hydrochloride;EINECS 224-237-6;3-Chloro-2-methylpropyl(dimethyl)ammonium chloride;N-(3-Chloro-2-methylpropyl)-N,N-dimethylamine hydrochloride;1-Dimethylamino-2-methyl-3-chloropropane hydrochloride;3-Dimethylamino-2-methylpropyl-d6ChlorideHydrochloride;(3-CHLORO-2-METHYLPROPYL)DIMETHYLAMINE HYDROCHLORIDE;3-Chloro-2-methyl-N,N-dimethylpropylamine hydrochloride;3-Dimethylamino-2-methylpropyl chloride HCl;SCHEMBL2218250;DTXSID60962610;SOMIBONUMGNAEP-UHFFFAOYSA-N;BCP09620;MFCD00012514;2-bromo-1,3-diphenyl-3-propanedione;CS-W017630;AS-69285;FT-0607606;3-Chloro-N,N,2-trimethylpropan-1-amine HCl;D71215;EN300-25979384;2-methyl-3-dimethylaminopropylchloride hydrochloride;3-chloro-N,N,2-trimethylpropan-1-aminehydrochloride;3-dimethylamino-2-methylpropylchloride hydrochloride;J-512396;2-methyl-3-dimethylaminopropyl chloride hydrochloride;3-chloro-2-methyl-1-dimethylaminopropane hydrochloride;3-chloro-N,N,2-trimethyl-1-propanamine hydrochloride;1-chloro-3-(dimethylamino)-2-methylpropane hydrochloride;3-Chloro-N,N,2-trimethylpropan-1-amine--hydrogen chloride (1/1)

Chemical Property of 3-Dimethylamino-2-methylpropyl chloride hydrochloride

Chemical Property:

• Appearance/Colour: white to off-white powder
• Vapor Pressure: 5.07mmHg at 25°C
• Melting Point: 169-173 °C
• Boiling Point: 144.5 °C at 760 mmHg
• Flash Point: 41.2 °C
• PSA: 3.24000
• LogP: 2.22490
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Sensitive.: Hygroscopic
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 171.0581549
• Heavy Atom Count: 9
• Complexity: 54.5

Purity/Quality:

99%min ^*data from raw suppliers

3-Dimethylamino-2-methylpropylChlorideHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 37/39-26

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(CN(C)C)CCl.Cl
• Uses: Cyamemazine intermediate.

Technology Process of 3-Dimethylamino-2-methylpropyl chloride hydrochloride

There total 1 articles about 3-Dimethylamino-2-methylpropyl chloride hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methyl-3-dimethylaminopropanol (33622-41-2) → 1-chloro-2-methyl-3-(dimethylamino)propane hydrochloride (4261-67-0)

Guidance literature:

With thionyl chloride; In chloroform; Reflux; Cooling with ice;

DOI:10.1002/pola.27048

Reference yield:

1-chloro-2-methyl-3-(dimethylamino)propane hydrochloride (4261-67-0) → 3-(dimethylamino)-2-methylpropylchloride (23349-86-2)

Guidance literature:

With sodium hydroxide; In water; pentane; at 20 ℃; for 1h;

Reference yield:

2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one (27068-88-8) + diethyl ether (60-29-7,927820-24-4) + water (7732-18-5) + potassium carbonate (584-08-7) + 1-chloro-2-methyl-3-(dimethylamino)propane hydrochloride (4261-67-0) → Cis(+)-3-acetyloxy-2,3-dihydro-5-(2-methyl-3-dimethylaminopropyl)-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one oxalate

Guidance literature:

With oxalic acid; acetic anhydride; In acetone;

upstream raw materials:

2-methyl-3-dimethylaminopropanol

Downstream raw materials:

Phenyl-2-propanon-(2-methyl-3-dimethylamino-propylhydrazon)

1-(2-Methyl-3-dimethylaminopropyl)-2-(1-phenyl-2-propyl)hydrazin

3-(dimethylamino)-2-methylpropylchloride

Refernces