4-Methoxybenzaldehyde O-methyl oxime

Base Information

• Chemical Name: 4-Methoxybenzaldehyde O-methyl oxime
• CAS No.: 33499-40-0
• Molecular Formula: C₉H₁₁NO₂
• Molecular Weight: 165.192
• Mol file: 33499-40-0.mol

Synonyms:4-Methoxybenzaldehyde O-methyl oxime

Chemical Property of 4-Methoxybenzaldehyde O-methyl oxime

Chemical Property:

Purity/Quality:

99.0%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-Methoxybenzaldehyde O-methyl oxime

There total 3 articles about 4-Methoxybenzaldehyde O-methyl oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

N-methoxylamine hydrochloride (593-56-6) + 4-methoxy-benzaldehyde (123-11-5) → 4-methoxybenzaldehyde O-methyl oxime (70286-37-2,87861-04-9,33499-40-0)

Guidance literature:

With sodium hydroxide; In methanol; water; at 0 - 20 ℃; for 1h;

DOI:10.1039/c6cc09379e

Reference yield: 88.0%

N-methoxylamine hydrochloride (593-56-6) + 4-Methoxybenzyl alcohol (105-13-5) → 4-methoxybenzaldehyde O-methyl oxime (70286-37-2,87861-04-9,33499-40-0)

Guidance literature:

With manganese(IV) oxide; 4 A molecular sieve; In dichloromethane; for 22h; Heating;

DOI:10.1055/s-2002-32949

Reference yield: 84.0%

p-methoxyl benzaldoxime (3717-21-3,3717-22-4,140461-28-5,140461-29-6,3235-04-9) + methyl iodide (74-88-4) → 4-methoxybenzaldehyde O-methyl oxime (70286-37-2,87861-04-9,33499-40-0)

Guidance literature:

With potassium carbonate; In acetone; for 24h; Reflux;

DOI:10.1002/chem.201704389

upstream raw materials:

N-methoxylamine hydrochloride

4-methoxy-benzaldehyde

4-Methoxybenzyl alcohol

p-methoxyl benzaldoxime

Refernces

• 1、 Bakulina, Olga,Bannykh, Anton,Dar'in, Dmitry,Krasavin, Mikhail. "Cyclic Hydroxamic Acid Analogues of Bacterial Siderophores as Iron-Complexing Agents prepared through the Castagnoli–Cushman Reaction of Unprotected Oximes". supporting information. p. 17667 - 17673. Retrieved 2017/12/26.
• 2、 Konakahara, Takeo,Matsuki, Masayuki,Sugimoto, Shinji,Sato, Kenji. "Stereoselective Synthesis of trans-2-Aryl-3-(2-pyridyl)aziridines from an α-Silyl Carbanion". . p. 1489 - 1494. Retrieved 2007/10/02.