Dihydroxyacetone phosphate

Base Information

• Chemical Name: Dihydroxyacetone phosphate
• CAS No.: 57-04-5
• Deprecated CAS: 2134-85-2
• Molecular Formula: C3H7O6P
• Molecular Weight: 170.059
• Hs Code.: 2919900090
• European Community (EC) Number: 200-308-7
• UNII: T7KF2T6W95
• DSSTox Substance ID: DTXSID6058768
• Nikkaji Number: J213.543D
• Wikipedia: Dihydroxyacetone_phosphate
• Wikidata: Q416915
• Metabolomics Workbench ID: 37815
• ChEMBL ID: CHEMBL1161998
• Mol file: 57-04-5.mol

Synonyms:3-Phosphate, Dihydroxyacetone;Dihydroxyacetone 3 Phosphate;Dihydroxyacetone 3-Phosphate;Dihydroxyacetone Phosphate;Phosphate, Dihydroxyacetone

Chemical Property of Dihydroxyacetone phosphate

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 409.066 °C at 760 mmHg
• Flash Point: 201.196 °C
• PSA: 113.87000
• Density: 1.732 g/cm³
• LogP: -1.34290
• Storage Temp.: ?20°C
• XLogP3: -2.5
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 4
• Exact Mass: 169.99802494
• Heavy Atom Count: 10
• Complexity: 158

Purity/Quality:

99% ^*data from raw suppliers

Glycerone phosphate lithium salt ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C(C(=O)COP(=O)(O)O)O
• Recent ClinicalTrials: Everolimus in Combination With DHAP in Patients With Relapsed or Refractory Hodgkin Lymphoma

Technology Process of Dihydroxyacetone phosphate

There total 33 articles about Dihydroxyacetone phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

cyclohexylamine (29909-08-8,102783-60-8) → dihydroxyacetone phosphate (57-04-5)

Guidance literature:

cyclohexylamine; In water;

With water; at 40 ℃; for 4h;

DOI:10.1016/j.carres.2009.12.008

Reference yield: 100.0%

dihydroxyacetone (96-26-4,26776-70-5) → dihydroxyacetone phosphate (57-04-5)

Guidance literature:

With phosphoenolpyruvic acid; ATP; for 0.75h; Enzymatic reaction;

DOI:10.1002/cctc.201500606

Reference yield: 99.0%

3-(benzyloxy)-2-oxopropyl dibenzylphosphate (796874-61-8) → dihydroxyacetone phosphate (57-04-5)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; water; at 20 ℃; for 1h; atmospheric pressure;

DOI:10.1021/ol061748a

upstream raw materials:

sn-glycerol 3-phosphate

1,1-dihydroxyacetone

fructose-1,6-bisphosphate

dihydroxyacetone

Downstream raw materials:

D-Fructose

Fructose-1-phosphate

L-fructose

L-Sorbose 1,6-bis(phosphate)

Refernces

• 1、 Campbell,Jones,Kiener,Waley. "Enzyme-substrate and enzyme-inhibitor complexes of triose phosphate isomerase studied by 31P nuclear magnetic resonance". . p. 607 - 621,609,613,614. Retrieved 1979.
• 2、 Gray. "". . p. 4705,4708. Retrieved 1971.
• 3、 Meyer, Odile,Ponaire, Sarah,Rohmer, Michel,Grosdemange-Billiard, Catherine. "Lewis acid mediated regioselective ring opening of benzylglycidol with dibenzyl phosphate: Short and attractive synthesis of dihydroxyacetone phosphate". . p. 4347 - 4350. Retrieved 2006.
• 4、 HEINZ,LAMPRECHT. "Concentration and characterization of a triosekinase from liver. On the biochemistry of fructose metabolism. III.". . p. 88 - 100. Retrieved 1961.
• 5、 Hecht,Kis,Eisenreich,Amslinger,Wungsintaweekul,Herz,Rohdich,Bacher. "Enzyme-assisted preparation of isotope-labeled 1-deoxy-D-xylulose 5-phosphate". . p. 3948 - 3952. Retrieved 2001.
• 6、 Fonvielle, Matthieu,Weber, Philippe,Dabkowska, Kasia,Therisod, Michel. "New highly selective inhibitors of class II fructose-1,6-bisphosphate aldolases". . p. 2923 - 2926. Retrieved 2004.
• 7、 Rohdich,Schuhr,Hecht,Herz,Wungsintaweekul,Eisenreich,Zenk,Bacher. "Biosynthesis of isoprenoids. A rapid method for the preparation of isotope-labeled 4-diphosphocytidyl-2C-methyl-D-erythritol". . p. 9571 - 9573. Retrieved 2000.
• 8、 Lou, Xiaorui,Zhang, Jianyu,Liu, Shimeng,Wang, Runhao,Li, Weiping,Liu, Ruihua,Zhang, Qionglin,Bartlam, Mark. "Structural characterization of an L-fuculose-1-phosphate aldolase from Klebsiella pneumoniae". . p. 15 - 19. Retrieved 2022/04/07.
• 9、 Huddleston, Jamison P.,Thoden, James B.,Dopkins, Brandon J.,Narindoshvili, Tamari,Fose, Blair J.,Holden, Hazel M.,Raushel, Frank M.. "Structural and functional characterization of ydji, an aldolase of unknown specificity in escherichia coli K12". . p. 3340 - 3353. Retrieved 2019/08/27.