3-Nitro-4-chlorophenyl azide

Base Information

• Chemical Name: 3-Nitro-4-chlorophenyl azide
• CAS No.: 13243-32-8
• Molecular Formula: C6H3ClN4O2
• Molecular Weight: 198.568
• Hs Code.: 2929909090
• European Community (EC) Number: 968-656-9
• Nikkaji Number: J1.524.450J
• Mol file: 13243-32-8.mol

Synonyms:4-AZIDO-1-CHLORO-2-NITROBENZENE;13243-32-8;3-Nitro-4-chlorophenyl azide;AKOS006229716;4-azido-1-chloro-2-nitrobenzene, AldrichCPR;EN300-8086196

Chemical Property of 3-Nitro-4-chlorophenyl azide

Chemical Property:

• PSA: 95.57000
• LogP: 3.16596
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 197.9944530
• Heavy Atom Count: 13
• Complexity: 248

Purity/Quality:

4-AZIDO-1-CHLORO-2-NITROBENZENE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C=C1N=[N+]=[N-])[N+](=O)[O-])Cl

Technology Process of 3-Nitro-4-chlorophenyl azide

There total 2 articles about 3-Nitro-4-chlorophenyl azide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-Chloro-3-nitroaniline (635-22-3) → 1-azido-3-nitro-4-chlorobenzene (13243-32-8)

Guidance literature:

Multistep reaction; (i) (diazotization), (ii) aq. NaN₃;

DOI:10.1039/j39660001980

Reference yield:

→ 1-azido-3-nitro-4-chlorobenzene (13243-32-8)

Guidance literature:

With sodium azide;

Reference yield: 95.0%

1-azido-3-nitro-4-chlorobenzene (13243-32-8) + 5,5-diphenyl-3-(prop-2-yn-1-yl)imidazolidine-2,4-dione (2718-07-2) → 3?[[1?(4?chloro?3?nitrophenyl)?1H?1,2,3?triazol?4?yl]methyl]?5,5?diphenylimidazolidine?2,4?dione

Guidance literature:

With copper(II) sulfate; sodium L-ascorbate; 4-amino-5-hydroxy-2,7-naphthalene-disulfonic acid, monosodium salt; In water; at 70 ℃; for 0.333333h; Reagent/catalyst; Solvent; Temperature;

DOI:10.1007/s00706-020-02616-3

upstream raw materials:

4-Chloro-3-nitroaniline

Downstream raw materials:

C₁₃H₁₁ClN₆O₂

4-chloro-1,3-phenylenediamine

4-Chloro-3-nitroaniline

Refernces

• 1、 Sravya,Padmavathi,Padmaja. "Synthesis and reactivity of 2-chloro-5-(4-phenyl-1H-1,2,3-triazol-1-yl) benzenamine". . p. 1619 - 1625. Retrieved 2015/02/02.