Acetamide, N-(7-chloro-2-fluorenyl)-

Base Information

• Chemical Name: Acetamide, N-(7-chloro-2-fluorenyl)-
• CAS No.: 5096-17-3
• Molecular Formula: C15H12 Cl N O
• Molecular Weight: 256.72
• Hs Code.: 2924299090
• NSC Number: 65925
• DSSTox Substance ID: DTXSID00198971
• Nikkaji Number: J33.413H
• Wikidata: Q83071853
• ChEMBL ID: CHEMBL314110
• Mol file: 5096-17-3.mol

Synonyms:n-(7-chloro-9h-fluoren-2-yl)acetamide;5096-17-3;Acetamide, N-(7-chloro-2-fluorenyl)-;N-(7-Chloro-2-fluorenyl)acetamide;N-2-(7-Chloro)fluorenylacetamide;Acetamide, N-(7-chloro-9H-fluoren-2-yl)-;NSC 65925;BRN 2809480;Acetamide, N-(7-chlorofluoren-2-yl)-;3-12-00-03292 (Beilstein Handbook Reference);NSC65925;NCIOpen2_003189;CHEMBL314110;DTXSID00198971;NSC-65925;WLN: L B656 HHJ EMV1 KG;LS-8541

Chemical Property of Acetamide, N-(7-chloro-2-fluorenyl)-

Chemical Property:

• Vapor Pressure: 5.55E-10mmHg at 25°C
• Refractive Index: 1.6330 (estimate)
• Boiling Point: 496.1°C at 760 mmHg
• Flash Point: 253.9°C
• PSA: 29.10000
• Density: 1.332g/cm³
• LogP: 3.94260
• XLogP3: 3.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 257.0607417
• Heavy Atom Count: 18
• Complexity: 333

Purity/Quality:

99% ^*data from raw suppliers

N-(7-CHLORO-2-FLUORENYL)ACETAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)NC1=CC2=C(C=C1)C3=C(C2)C=C(C=C3)Cl

Technology Process of Acetamide, N-(7-chloro-2-fluorenyl)-

There total 3 articles about Acetamide, N-(7-chloro-2-fluorenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

7-chloro-2-nitrofluorene (6939-05-5) → N-(7-chloro-fluoren-2-yl)-acetamide (5096-17-3)

Guidance literature:

Multi-step reaction with 2 steps

1: zinc; aqueous ethanol

2: acetic acid

With ethanol; acetic acid; zinc;

DOI:10.1021/jo01155a007

Reference yield:

2-chloro-9H-fluorene (2523-44-6) → N-(7-chloro-fluoren-2-yl)-acetamide (5096-17-3)

Guidance literature:

Multi-step reaction with 3 steps

1: aqueous HNO₃

2: zinc; aqueous ethanol

3: acetic acid

With ethanol; nitric acid; acetic acid; zinc;

DOI:10.1021/jo01155a007

Reference yield:

7-chloro-fluoren-2-ylamine (6957-62-6) + acetic anhydride (108-24-7) → N-(7-chloro-fluoren-2-yl)-acetamide (5096-17-3)

Guidance literature:

With acetic acid;

DOI:10.1021/jo01155a007

upstream raw materials:

7-chloro-fluoren-2-ylamine

acetic anhydride

7-chloro-2-nitrofluorene

2-chloro-9H-fluorene

Downstream raw materials:

N-(3,7-dichloro-fluoren-2-yl)-acetamide

2,3,7-Trichlor-fluorenon

2,7-Dichlor-3-nitro-fluorenon

3,7-dichloro-fluoren-2-ylamine