6-DEOXY-BETA-L-GALACTOSE PHOSPHATE DI(CYCLOHEXYLAMMONIUM SALT)

Base Information

• Chemical Name: 6-DEOXY-BETA-L-GALACTOSE PHOSPHATE DI(CYCLOHEXYLAMMONIUM SALT)
• CAS No.: 28553-11-9
• Molecular Formula: C₆H₁₃O₈P
• Molecular Weight: 244.138
• Hs Code.: 29400090
• Mol file: 28553-11-9.mol

Synonyms:6-DEOXY-BETA-L-GALACTOSE PHOSPHATE DI(CYCLOHEXYLAMMONIUM SALT);BETA-L-FUCOSE 1-PHOSPHATE DI(CYCLOHEXYLAMMONIUM SALT);B-L-FUCOSE 1-PHOSPHATE DI(CYCLOHEXYL-*AM MONIUM);6-deoxy-β-l-galactose phosphate;β-l-fucose 1-phosphate bis(cyclohexylammonium) salt;b-L-Fucose-1-phosphatebis(cyclohexylammonium)salt;fucopyranosyl phosphate;6-Deoxy-β-L-galactose 1-phosphate

Chemical Property of 6-DEOXY-BETA-L-GALACTOSE PHOSPHATE DI(CYCLOHEXYLAMMONIUM SALT)

Chemical Property:

• Vapor Pressure: 5.83E-13mmHg at 25°C
• Boiling Point: 519.4°C at 760 mmHg
• Flash Point: 267.9°C
• PSA: 146.49000
• Density: 1.75g/cm³
• LogP: -2.07680
• Storage Temp.: −20°C

Purity/Quality:

99%, ^*data from raw suppliers

β--Fucose-1-phosphatebis(cyclohexylammonium)salt ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-DEOXY-BETA-L-GALACTOSE PHOSPHATE DI(CYCLOHEXYLAMMONIUM SALT)

There total 37 articles about 6-DEOXY-BETA-L-GALACTOSE PHOSPHATE DI(CYCLOHEXYLAMMONIUM SALT) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

Ag2 CO3 + ? molecular sieves + phosphoric acid dibenzyl ester (1623-08-1) + 3,4-di-O-acetyl-2,6-dideoxy-2-fluoro-α-L-galactopyranosyl bromide (186186-65-2) → β-L-Fucopyranosyl phosphate (16562-59-7,28553-11-9)

Guidance literature:

In benzene;

Reference yield: 60.4%

D-Fucose (73-34-7,87-96-7,488-79-9,551-63-3,609-01-8,643-17-4,643-18-5,4164-09-4,6014-42-2,6155-36-8,6189-71-5,6696-41-9,6736-43-2,13224-93-6,22611-09-2,28161-49-1,28161-50-4,28161-52-6,45864-36-6,63814-64-2,71116-59-1,71116-61-5,72598-05-1,87936-88-7,87936-89-8,97466-79-0,116908-82-8,120442-60-6,123484-22-0,133576-32-6) → Gal6deoxy-1-P (81276-27-9,28553-11-9)

Guidance literature:

With hydrogenchloride; Bifidobacterium infantis ATCC₁₅₆₉₇ galactokinase; ATP; 2-amino-2-hydroxymethyl-1,3-propanediol; magnesium chloride; In water; at 37 ℃; for 12h; pH=6.5; Enzymatic reaction;

DOI:10.1039/c5cc03746h

Reference yield:

2,3,4-tri-O-acetyl-α-L-fucopyranosyl bromide (16741-27-8) → L-fucose-1-phosphate (16562-58-6,28553-11-9)

Guidance literature:

Multi-step reaction with 2 steps

1: dimethylformamide / 0.17 h / 23 °C

In N,N-dimethyl-formamide;

DOI:10.1139/v90-165

upstream raw materials:

dibenzyl-(2,3,4-tri-O-benzyl-6-deoxy-α-D-glucopyranosyl) phosphate

6-deoxy-D-glucose

methyl-alpha-D-glucopyranoside

methyl 6-chloro-6-deoxy-α-D-glucopyranoside

Downstream raw materials:

guanosine-5'-diphospho-β-L-fucose

dTDP-β-L-fucose

UDP-β-L-fucose

uridine 5'-(6-deoxy-α-D-glucopyranosyl diphosphate)

Refernces

• 1、 Li, Lei,Liu, Yonghui,Wang, Wenjun,Cheng, Jiansong,Zhao, Wei,Wang, Peng. "A highly efficient galactokinase from Bifidobacterium infantis with broad substrate specificity". experimental part. p. 35 - 39. Retrieved 2012/08/08.
• 2、 Ren, Yan,Perepelov, Andrei V.,Wang, Haiyan,Zhang, Hao,Knirel, Yuriy A.,Wang, Lei,Chen, Wei. "Biochemical characterization of GDP-l-fucose de novo synthesis pathway in fungus Mortierella alpina". scheme or table. p. 1663 - 1669. Retrieved 2011/02/27.