(S)-2-(Methoxycarbonylamino)-2-(tetrahydro-2H-pyran-4-yl)ethanoic acid

Base Information Edit

Chemical Name:(S)-2-(Methoxycarbonylamino)-2-(tetrahydro-2H-pyran-4-yl)ethanoic acid
CAS No.:1009120-03-9
Molecular Formula:C9H15NO5
Molecular Weight:217.222
Hs Code.:
Mol file:1009120-03-9.mol

Synonyms:(S)-2-(Methoxycarbonylamino)-2-(tetrahydro-2H-pyran-4-yl)ethanoic acid

Suppliers and Price of (S)-2-(Methoxycarbonylamino)-2-(tetrahydro-2H-pyran-4-yl)ethanoic acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(S)-Methyl2-((methoxycarbonyl)amino)-2-(tetrahydro-2H-pyran-4-yl)acetate 97%
10g
$ 358.00

Crysdot
(S)-Methyl2-((methoxycarbonyl)amino)-2-(tetrahydro-2H-pyran-4-yl)acetate 97%
25g
$ 647.00

Chemenu
methyl(S)-2-((methoxycarbonyl)amino)-2-(tetrahydro-2H-pyran-4-yl)acetate 97%
25g
$ 611.00

Chemenu
methyl(S)-2-((methoxycarbonyl)amino)-2-(tetrahydro-2H-pyran-4-yl)acetate 97%
10g
$ 338.00

Total 9 raw suppliers

Chemical Property of (S)-2-(Methoxycarbonylamino)-2-(tetrahydro-2H-pyran-4-yl)ethanoic acid Edit

Chemical Property:

Boiling Point:409.9±20.0 °C(Predicted)
PKA:4.26±0.10(Predicted)
PSA：84.86000
Density:1 +-.0.06 g/cm3(Predicted)
LogP:0.61310

Purity/Quality:

98%Min ^*data from raw suppliers

(S)-Methyl2-((methoxycarbonyl)amino)-2-(tetrahydro-2H-pyran-4-yl)acetate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (S)-2-(Methoxycarbonylamino)-2-(tetrahydro-2H-pyran-4-yl)ethanoic acid

There total 6 articles about (S)-2-(Methoxycarbonylamino)-2-(tetrahydro-2H-pyran-4-yl)ethanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 811842-25-8,475649-32-2
(S)-2-amino-2-(tetrahydro-2 H-pyran-4-yl)acetic acid

: 79-22-1
methyl chloroformate

: 1009120-03-9
(S)-methoxycarbonylamino(tetrahydropyran-4-yl)acetic acid

Guidance literature:: With sodium hydrogencarbonate; In water; Inert atmosphere;

Reference yield: 86.0%

: 1257239-30-7
C₁₀H₁₇NO₅

: 1009120-03-9
(S)-methoxycarbonylamino(tetrahydropyran-4-yl)acetic acid

Guidance literature:: C₁₀H₁₇NO₅; With lithium hydroxide monohydrate; In tetrahydrofuran; water; at 20 ℃; for 2h;

With hydrogenchloride; In water;

Reference yield:

: 29943-42-8,143562-54-3
Tetrahydro-4H-pyran-4-one

: 1009120-03-9
(S)-methoxycarbonylamino(tetrahydropyran-4-yl)acetic acid

Guidance literature:: Multi-step reaction with 5 steps

1.1: N,N,N',N'-tetramethylguanidine / tetrahydrofuran / 1 h / -20 °C

1.2: -20 - 20 °C

2.1: hydrogen / 1,2-bis[(2S,5S)-2,5-(dimethylphospholano)]-ethane-(cyclooctadiene)rhodium(I) tetrafluoroborate / methanol / 18 h / 2585.81 Torr / Inert atmosphere

3.1: hydrogen / palladium on activated charcoal / methanol / 2 h / Inert atmosphere

4.1: triethylamine / dichloromethane / 15 h / 20 °C

5.1: water; lithium hydroxide monohydrate / tetrahydrofuran / 2 h / 20 °C

With lithium hydroxide monohydrate; water; hydrogen; triethylamine; N,N,N',N'-tetramethylguanidine; 1,2-bis[(2S,5S)-2,5-(dimethylphospholano)]-ethane-(cyclooctadiene)rhodium(I) tetrafluoroborate; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane;