6-deoxy-6-fluoroglucose

Base Information

• Chemical Name: 6-deoxy-6-fluoroglucose
• CAS No.: 4536-08-7
• Molecular Formula: C₆H₁₁FO₅
• Molecular Weight: 182.149
• Hs Code.: 2913000090
• Mol file: 4536-08-7.mol

Synonyms:Glucose,6-deoxy-6-fluoro-, D- (8CI); 6-Deoxy-6-fluoro-D-glucose;6-Deoxy-6-fluoroglucose; D-Glucose 6-fluorohydrin

Chemical Property of 6-deoxy-6-fluoroglucose

Chemical Property:

• Vapor Pressure: 2.25E-10mmHg at 25°C
• Melting Point: 120-126°C
• Boiling Point: 459.5°Cat760mmHg
• Flash Point: 231.7°C
• PSA: 97.99000
• Density: 1.494g/cm³
• LogP: -2.40160
• Storage Temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

Purity/Quality:

99%, ^*data from raw suppliers

6-Deoxy-6-fluoro-D-glucose ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 6-Deoxy-6-fluoro-D-glucose (cas# 4536-08-7) is a compound useful in organic synthesis.

Technology Process of 6-deoxy-6-fluoroglucose

There total 3 articles about 6-deoxy-6-fluoroglucose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 6-fluoro-6-deoxyglucosse (4536-08-7)

Guidance literature:

With sulfuric acid;

Reference yield:

(6-deoxy-6-fluoro)hexakiscyclomaltoheptaose (99552-37-1) → 6-fluoro-6-deoxyglucosse (4536-08-7) + 4-O-(6'-deoxy-6'-fluoro-α-D-glucopyranosyl)-β-D-glucopyranoside + 4-O-(α-D-glucopyranosyl)-6-deoxy-6-fluoro-β-D-glucopyranoside

Guidance literature:

With porcine-pancreatic alpha amylase; water; at 37 ℃; for 120h; Product distribution; buffer (sodium glycerophosphate, NaCl, NaN3), pH = 6.9; product analysis by radiotracer techniques after reduction with <3H> borohydride;

DOI:10.1016/S0008-6215(00)90700-6

Reference yield:

(6-deoxy-6-fluoro)hexakiscyclomaltoheptaose (99552-37-1) → D-glucose (50-99-7) + 6-fluoro-6-deoxyglucosse (4536-08-7)

Guidance literature:

With oxonium; Product distribution; determination of structure;

DOI:10.1016/S0008-6215(00)90700-6

upstream raw materials:

(6-deoxy-6-fluoro)hexakiscyclomaltoheptaose

Downstream raw materials:

6-fluoro-D-arabino-6-deoxy-[2]hexosulose-bis-phenylhydrazone

1,2,3,4-tetra-O-acetyl-6-deoxy-6-fluoro-β-D-glucopyranose

1,2,3,4-tetra-O-acetyl-6-deoxy-6-fluoro-α-D-glucopyranose

Refernces