Lysidine

Base Information

• Chemical Name: Lysidine
• CAS No.: 534-26-9
• Molecular Formula: C4H8N2
• Molecular Weight: 84.1209
• Hs Code.: 2933290090
• European Community (EC) Number: 208-596-6
• UNII: 987F50E3PE
• DSSTox Substance ID: DTXSID2060204
• Nikkaji Number: J2.631J
• Wikipedia: Lysidine_(chemical)
• Wikidata: Q423614
• ChEMBL ID: CHEMBL3935635
• Mol file: 534-26-9.mol

Synonyms:4-amino-2-(N(6)-lysino)-1-ribofuranosylpyrimidine;lysidine

Chemical Property of Lysidine

Chemical Property:

• Appearance/Colour: light yellow to Off-white crystalline
• Vapor Pressure: 0.493mmHg at 25°C
• Melting Point: 87 °C (dec.)(lit.)
• Refractive Index: 1.5037 (estimate)
• Boiling Point: 144°C 140mm
• PKA: 10.98±0.40(Predicted)
• Flash Point: 74.2 °C
• PSA: 24.39000
• Density: 1.1 g/cm³
• LogP: -0.22760
• Water Solubility.: Soluble in water, alcohol, chloroform.
• XLogP3: 0.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 84.068748264
• Heavy Atom Count: 6
• Complexity: 75.6

Purity/Quality:

99%, ^*data from raw suppliers

2-Methyl-2-imidazoline ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC1=NCCN1
• Uses: 2-Methyl-2-imidazoline can be used as corrosion inhibitor.

Technology Process of Lysidine

There total 29 articles about Lysidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-methyl-1,4,5,6-tetrahydropyrimidine (4271-95-8) + ethylenediamine (107-15-3,85404-18-8) → lysidine (534-26-9)

Guidance literature:

Heating;

Reference yield: 85.0%

acetic acid (64-19-7,77671-22-8) + ethylenediamine (107-15-3,85404-18-8) → lysidine (534-26-9)

Guidance literature:

With iron oxide; In water; benzene; at 80 ℃; for 3h;

DOI:10.1134/S1070363216020122

Reference yield: 80.0%

C22H23N2OP (99378-98-0) → lysidine (534-26-9) + Triphenylphosphine oxide (791-28-6)

Guidance literature:

at 180 ℃; for 5h;

DOI:10.1016/S0040-4020(01)96459-2

upstream raw materials:

imidazolidone

monoacetylaminoethylamine

N,N'-diacetylethylenediamine

sodium acetate

Downstream raw materials:

acetaldehyde

2-(4-nitro-styryl)-4,5-dihydro-1H-imidazole

1-benzyl-2-methyl-4,5-dihydro-1H-imidazole

ammonia

Refernces

• 1、 -. "METHOD FOR PRODUCING IMIDAZOLINE COMPOUND". Paragraph 0045; 0049-0051; 0059-0066; 0069-0070. . Retrieved 2021/06/04.
• 2、 -. "INTRACELLULAR DELIVERY VEHICLE". Paragraph 0292. . Retrieved 2019/05/18.