2-AMINO-3,5-DIBROMO-6-METHYLPYRIDINE

Base Information

• Chemical Name: 2-AMINO-3,5-DIBROMO-6-METHYLPYRIDINE
• CAS No.: 91872-10-5
• Molecular Formula: C6H6Br2N2
• Molecular Weight: 265.935
• Hs Code.: 29333990
• Mol file: 91872-10-5.mol

Synonyms:3,5-Dibromo-6-methyl-2-pyridinamine;

Chemical Property of 2-AMINO-3,5-DIBROMO-6-METHYLPYRIDINE

Chemical Property:

• Appearance/Colour: Off-white powder
• Vapor Pressure: 0.0115mmHg at 25°C
• Melting Point: 143.5-148.5 °C(lit.)
• Boiling Point: 261.6 °C at 760 mmHg
• PKA: 2.04±0.50(Predicted)
• Flash Point: 112 °C
• PSA: 38.91000
• Density: 1.99 g/cm³
• LogP: 3.07840
• Storage Temp.: Room temperature.
• Solubility.: slightly sol. in Methanol

Purity/Quality:

99% ^*data from raw suppliers

2-Amino-3,5-dibromo-6-methylpyridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi, Xn
• Hazard Codes: Xi,Xn
• Statements: 36/37/38-20/21/22
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: 2-Amino-3,5-dibromo-6-methylpyridine may be used to synthesize 1-[[(3,5-dibromo-6-methyl-2-pyridinyl)imino]-methylenyl]-2-naphthalenol and 3,5-dibromo-6-methyl-2-pyridone.

Technology Process of 2-AMINO-3,5-DIBROMO-6-METHYLPYRIDINE

There total 2 articles about 2-AMINO-3,5-DIBROMO-6-METHYLPYRIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

2-Amino-6-methylpyridine (1824-81-3) → 5-bromo-6-methyl-pyridin-2-ylamine (42753-71-9) + 2-amino-3,5-dibromo-6-methylpyridine (91872-10-5) + 2-amino-3-bromo-6-methyl-pyridine (126325-46-0)

Guidance literature:

With hydrogen bromide; dihydrogen peroxide; at 70 ℃; for 1h; Product distribution;

Reference yield: 5.0%

2-Amino-6-methylpyridine (1824-81-3) → 5-bromo-6-methyl-pyridin-2-ylamine (42753-71-9) + 2-amino-3,5-dibromo-6-methylpyridine (91872-10-5)

Guidance literature:

With bromine; In acetic acid; at 20 ℃; for 1h;

Reference yield: 88.0%

2-amino-3,5-dibromo-6-methylpyridine (91872-10-5) + 2-methyl-benzyl alcohol (89-95-2) → 2-[[(3,5-dibromo-6-methylpyridin-2-yl)imino]methyl]-phenol

Guidance literature:

at 20 ℃; for 0.0666667h; microwave irradiation;

DOI:10.1081/SCC-120006012

upstream raw materials:

2-Amino-6-methylpyridine

Downstream raw materials:

3,5-dibromo-2-chloro-6-methyl-pyridine

N-(3,5-dibromo-6-methylpyridin-2-yl)benzamide

C₁₃H₉BrN₂S

6,8-dibromo-3-(2-ethoxy-benzoylamino)-5-methyl-imidazo[1,2-a]pyridine-2-carboxylic acid amide

Refernces

• 1、 Lindstroem, Stefan,Ahmad, Tania,Grivas, Spiros. "SYNTHESIS OF THE MUTAGENIC 2-AMINO-1,6-DIMETHYLIMIDAZOPYRIDINE (1,6-DMIP) AND FIVE OF ITS ISOMERS". . p. 529 - 540. Retrieved 2007/10/02.