Technology Process of 1-[3-(4-Benzhydrylpiperazin-1-ium-1-yl)propyl]benzimidazol-2-olate
There total 10 articles about 1-[3-(4-Benzhydrylpiperazin-1-ium-1-yl)propyl]benzimidazol-2-olate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
triethylamine; potassium iodide;
In
toluene;
for 20h;
Heating;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 62 percent / anh. K2CO3, KI, methyl isobutylacetone / Heating
2: CaCl2 / 1.5 h / 210 °C
With
rac-4-methyl-5-methylhexan-2-one; potassium carbonate; potassium iodide; calcium chloride;
DOI:10.1007/BF00798789
- Guidance literature:
-
Multi-step reaction with 4 steps
1: xylene / 18 h / Heating
2: 90 percent / anh. K2CO3, KI, methyl isobutyl acetone / Heating
3: H2 / 10percent Pd/C / methanol / 4 h
4: CaCl2 / 1.5 h / 210 °C
With
3,5-dimethyl-hexan-2-one; hydrogen; potassium carbonate; potassium iodide; calcium chloride;
palladium on activated charcoal;
In
methanol; xylene;
DOI:10.1007/BF00798789