Technology Process of Homomoschatoline
There total 9 articles about Homomoschatoline which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
(2-aminophenyl)(5,6,7-trimethoxyisoquinolin-1-yl)methanone;
With
sulfuric acid; sodium nitrite;
In
water;
at 0 - 8 ℃;
for 0.25h;
With
copper;
In
water;
at 60 ℃;
DOI:10.1039/c8ra05338c
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: trichlorophosphate / acetonitrile / 2 h / Reflux
2.1: 1,8-diazabicyclo[5.4.0]undec-7-ene; copper(ll) bromide; oxygen / dimethyl sulfoxide / 8 h / 35 °C / Green chemistry
3.1: iron; acetic acid / water; ethanol / 70 °C / Inert atmosphere
4.1: sulfuric acid; sodium nitrite / water / 0.25 h / 0 - 8 °C
4.2: 60 °C
With
sulfuric acid; oxygen; iron; acetic acid; 1,8-diazabicyclo[5.4.0]undec-7-ene; copper(ll) bromide; sodium nitrite; trichlorophosphate;
In
ethanol; water; dimethyl sulfoxide; acetonitrile;
1.1: |Bischler-Napieralski Reaction;
DOI:10.1039/c8ra05338c
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: iron; acetic acid / water; ethanol / 70 °C / Inert atmosphere
2.1: sulfuric acid; sodium nitrite / water / 0.25 h / 0 - 8 °C
2.2: 60 °C
With
sulfuric acid; iron; acetic acid; sodium nitrite;
In
ethanol; water;
DOI:10.1039/c8ra05338c
