Technology Process of 7-Amino-2-methylsulfanyl-5-oxo-8-phenyl-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide
There total 5 articles about 7-Amino-2-methylsulfanyl-5-oxo-8-phenyl-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
In
butan-1-ol;
Reflux;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: triethylamine / tetrahydrofuran / 20 °C
2.1: sodium hydroxide; water / ethanol / 20 °C
3.1: triethylamine; trifluoro-[1,3,5]triazine / dichloromethane / 20 °C
4.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.17 h / 0 - 20 °C
4.2: 20 °C / Cooling with ice
4.3: 5 h / 20 °C / Cooling with ice
5.1: butan-1-ol / Reflux
With
trifluoro-[1,3,5]triazine; water; sodium hydride; triethylamine; sodium hydroxide;
In
tetrahydrofuran; ethanol; dichloromethane; N,N-dimethyl-formamide; mineral oil; butan-1-ol;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sodium hydroxide; water / ethanol / 20 °C
2.1: triethylamine; trifluoro-[1,3,5]triazine / dichloromethane / 20 °C
3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.17 h / 0 - 20 °C
3.2: 20 °C / Cooling with ice
3.3: 5 h / 20 °C / Cooling with ice
4.1: butan-1-ol / Reflux
With
trifluoro-[1,3,5]triazine; water; sodium hydride; triethylamine; sodium hydroxide;
In
ethanol; dichloromethane; N,N-dimethyl-formamide; mineral oil; butan-1-ol;