Diethyl acetamidomalonate

Base Information Edit

Chemical Name:Diethyl acetamidomalonate
CAS No.:1068-90-2
Deprecated CAS:2088923-16-2
Molecular Formula:C9H15NO5
Molecular Weight:217.222
Hs Code.:2924.10
European Community (EC) Number:213-952-9
NSC Number:7645
UNII:4VDX81E00W
DSSTox Substance ID:DTXSID6061446
Nikkaji Number:J41.609F
ChEMBL ID:CHEMBL3278808
Mol file:1068-90-2.mol

Synonyms:DEAMA;diethyl acetamidomalonic acid;diethyl acetamidomalonic acid, 2-(13)C-labeled;diethylacetamidomalonate;diethylacetamidomalonic acid

Suppliers and Price of Diethyl acetamidomalonate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Diethyl2-Acetamidomalonate
500g
$ 145.00

TCI Chemical
Diethyl Acetamidomalonate >98.0%(GC)
100g
$ 32.00

TCI Chemical
Diethyl Acetamidomalonate >98.0%(GC)
25g
$ 16.00

TCI Chemical
Diethyl Acetamidomalonate >98.0%(GC)
500g
$ 114.00

Sigma-Aldrich
Diethyl acetamidomalonate 98%
500g
$ 172.00

Sigma-Aldrich
Diethyl acetamidomalonate 98%
100g
$ 39.50

Sigma-Aldrich
Diethyl acetamidomalonate 98%
25g
$ 19.50

Oakwood
Diethyl acetamidomalonate
25g
$ 15.00

Oakwood
Diethyl acetamidomalonate
5g
$ 10.00

Oakwood
Diethyl acetamidomalonate
100g
$ 20.00

Total 193 raw suppliers

Chemical Property of Diethyl acetamidomalonate Edit

Chemical Property:

Appearance/Colour:White crystalline powder
Vapor Pressure:0.000565mmHg at 25°C
Melting Point:93 - 96 ºC
Refractive Index:1.447
Boiling Point:311.4 ºC at 760 mmHg
PKA:11.93±0.59(Predicted)
Flash Point:145.2ºC
PSA：81.70000
Density:1.141 g/cm³
LogP:0.00820
Storage Temp.:Store at RT.
Solubility.:Chloroform (Slightly), Methanol (Slightly)
Water Solubility.:Soluble in chloroform and methanol. Slightly soluble in water.
XLogP3:0.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:217.09502258
Heavy Atom Count:15
Complexity:233

Purity/Quality:

99.0% ^*data from raw suppliers

Diethyl2-Acetamidomalonate ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36-36/37/38
Safety Statements: 39-36-26-44

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Chemical Classes:Nitrogen Compounds -> Other Nitrogen Compounds
Canonical SMILES:CCOC(=O)C(C(=O)OCC)NC(=O)C
Uses Diethyl 2-Acetamidomalonate, is a versatile building block used for the synthesis of various pharmaceutical and biologically active compounds. It is an intermediate for the preparation of Novobiocin analogues as potential heat shock protein 90 inhibitors. It is also used as a important intermediates in syntheses of vitamins B1 and B6, barbiturates, non-steroidal anti-inflammatory agents, other numerous pharmaceuticals.

Technology Process of Diethyl acetamidomalonate

There total 26 articles about Diethyl acetamidomalonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%