Dinotefuran

Base Information

• Chemical Name: Dinotefuran
• CAS No.: 165252-70-0
• Deprecated CAS: 222540-72-9
• Molecular Formula: C7H14N4O3
• Molecular Weight: 202.213
• Hs Code.: 29329990
• Wikidata: Q3028468
• ChEMBL ID: CHEMBL2228155
• Mol file: 165252-70-0.mol

Synonyms:Guanidine,N-methyl-N'-nitro-N''-[(tetrahydro-3-furanyl)methyl]- (9CI);Albarin;MTI 446;Mikeblock;Safari (insecticide);Starkle;Venom(insecticide);

Chemical Property of Dinotefuran

Chemical Property:

• Appearance/Colour: white crystalline powder
• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 107.5oC
• Refractive Index: 1.596
• Boiling Point: 334.5 °C at 760 mmHg
• PKA: 3.24±0.50(Predicted)
• Flash Point: 156.1 °C
• PSA: 91.47000
• Density: 1.42 g/cm³
• LogP: 0.68460
• Storage Temp.: 0-6°C
• Solubility.: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
• Water Solubility.: 39.83g/L at 20℃
• XLogP3: 0
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 202.10659032
• Heavy Atom Count: 14
• Complexity: 226

Purity/Quality:

99%+ ^*data from raw suppliers

Dinotefuran ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn,N
• Hazard Codes: Xn,N
• Statements: 22-53-56-57
• Safety Statements: 61

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CN=C(NCC1CCOC1)N[N+](=O)[O-]
• Description: Dinotefuran is a broad-spectrum insecticide, which is proposed for food uses in/on leafy vegetables (except Brassica) (group 4), and for use in professional turf management, professional ornamental production, and in the residential indoor, pet, lawn and garden markets. Dinotefuran is a neonicotinoid in the nitroguanidine sub-class, same as another insecticide clothianidin.
• Uses: Dinotefuran is a contact insecticide without systemic effect that belongs to the chemical class of the neonicotinoids, which are among the most widely used insecticides in the world. It is highly effective against fleas but not against ticks or mites, or any internal parasites.It is often used in combination with a tickicide/acaricide (e.g. permethrin) or with an insect growth regulator (e.g. pyriproxyfen). So far it is not used in livestock or horses. Dinotefuran is a neonicotinoid insecticide. Useful in cannabis testing kits as a component of pesticide mixes (P698240).

Technology Process of Dinotefuran

There total 3 articles about Dinotefuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

C2H7N5O2 + acetylacetone (123-54-6,81235-32-7) + (tetrahydro-3-furanyl)methylamine (165253-31-6,1048962-84-0) → 3,5-dimethyl-1H-pyrazole (67-51-6) + dinetofuran (165252-70-0)

Guidance literature:

C₂H₇N₅O₂; acetylacetone; With formic acid; In toluene; at 100 ℃; for 1h; Molecular sieve;

(tetrahydro-3-furanyl)methylamine; In toluene; at 100 ℃; for 2h; Molecular sieve;

Reference yield: 93.3%

1,1,1,5,5,5-hexafluoroacetylacetone (1522-22-1) + C2H7N5O2 + (tetrahydro-3-furanyl)methylamine (165253-31-6,1048962-84-0) → dinetofuran (165252-70-0) + 3,5-bis(trifluoromethyl)pyrazole (14704-41-7)

Guidance literature:

1,1,1,5,5,5-hexafluoroacetylacetone; C₂H₇N₅O₂; With formic acid; In toluene; at 60 ℃; for 1h; Molecular sieve;

(tetrahydro-3-furanyl)methylamine; In toluene; at 60 ℃; for 2h; Molecular sieve;

Reference yield: 83.1%

Malondialdehyde (542-78-9) + C2H7N5O2 + (tetrahydro-3-furanyl)methylamine (165253-31-6,1048962-84-0) → NH-pyrazole (288-13-1) + dinetofuran (165252-70-0)

Guidance literature:

Malondialdehyde; C₂H₇N₅O₂; With formic acid; In toluene; at 60 ℃; for 1h; Molecular sieve;

(tetrahydro-3-furanyl)methylamine; In toluene; at 60 ℃; for 2h; Molecular sieve;

upstream raw materials:

acetylacetone

(tetrahydro-3-furanyl)methylamine

1,1,1,5,5,5-hexafluoroacetylacetone

Malondialdehyde

Refernces