phenyl 4-ethoxycarbonyl phenyl

Base Information

• Chemical Name: phenyl 4-ethoxycarbonyl phenyl
• CAS No.: 1268380-09-1
• Molecular Formula: C₁₆H₁₄O₅
• Molecular Weight: 286.284
• Mol file: 1268380-09-1.mol

Synonyms:phenyl 4-ethoxycarbonyl phenyl

Chemical Property of phenyl 4-ethoxycarbonyl phenyl

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of phenyl 4-ethoxycarbonyl phenyl

There total 1 articles about phenyl 4-ethoxycarbonyl phenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Ethyl 4-hydroxybenzoate (120-47-8) + phenyl chloroformate (1885-14-9) → phenyl 4-ethoxycarbonyl phenyl (1268380-09-1)

Guidance literature:

With triethylamine; In diethyl ether;

DOI:10.5012/bkcs.2010.31.7.2015

Reference yield: 100.0%

phenyl 4-ethoxycarbonyl phenyl (1268380-09-1) → sodium salicylat (81256-74-8) + sodium salt of ethyl-4-hydroxybenzoate (35285-68-8)

Guidance literature:

With water; sodium hydroxide; In dimethyl sulfoxide; at 25 ℃; Kinetics;

DOI:10.5012/bkcs.2010.31.7.2015

Reference yield:

phenyl 4-ethoxycarbonyl phenyl (1268380-09-1) + potassium ethoxide (917-58-8) → C9H9O3(1-)*K(1+) (36457-19-9) + ethyl phenyl carbonate (3878-46-4)

Guidance literature:

In ethanol; at 25 ℃; Concentration; Reagent/catalyst; Kinetics; Mechanism;

DOI:10.1246/bcsj.20120104

upstream raw materials:

Ethyl 4-hydroxybenzoate

phenyl chloroformate

Downstream raw materials:

sodium salicylat

sodium salt of ethyl-4-hydroxybenzoate

phenyl carbonic acid

4-hydroxy-benzoic acid ethyl ester; deprotonated form

Refernces

• 1、 Park, Kyoung-Ho,Kim, Min-Young,Um, Ik-Hwan. "Kinetic study on nucleophilic displacement reactions of phenyl Y-substituted phenyl carbonates with 1,8-diazabicyclo[5.4.0]undec-7-ene: Effects of amine nature on reaction mechanism". . p. 77 - 81. Retrieved 2016/01/20.
• 2、 Kang, Ji-Sun,Song, Yoon-Ju,Um, Ik-Hwan. "Leaving-group substituent controls reactivity and reaction mechanism in aminolysis of phenyl y-substituted-phenyl carbonates". . p. 2023 - 2028. Retrieved 2013/09/02.