Prostaglandin I2; Prostacyclin

Base Information

• Chemical Name: Prostaglandin I2; Prostacyclin
• CAS No.: 61849-14-7
• Molecular Formula: C20H31O5^.Na
• Molecular Weight: 374.4469
• Hs Code.: 29329900
• European Community (EC) Number: 263-273-7
• Mol file: 61849-14-7.mol

Synonyms:61849-14-7;Epoprostenol (sodium);Prostaglandin I2;Prostacyclin;Prostaglandin I2 (sodium salt);Prostacyclin (sodium salt);Flolan;BCP15848;PD156244;Prostaglandin I(2);Prostacyclin sodium salt

Chemical Property of Prostaglandin I2; Prostacyclin

Chemical Property:

• Appearance/Colour: white crystalline powder
• Vapor Pressure: 1.86E-13mmHg at 25°C
• Melting Point: 168-170 °C
• Boiling Point: 530.2 °C at 760 mmHg
• Flash Point: 182.1 °C
• PSA: 89.82000
• LogP: 2.07380
• Storage Temp.: −20°C
• Sensitive.: Moisture Sensitive
• Solubility.: H2O: 1 mg/mL Hydrolyzes to 6-ketoprostaglandin F1α in
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 10
• Exact Mass: 374.20691837
• Heavy Atom Count: 26
• Complexity: 491

Purity/Quality:

99% ^*data from raw suppliers

PGI2 ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 20/21/22
• Safety Statements: 22-26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCCCCC(C=CC1C(CC2C1CC(=CCCCC(=O)[O-])O2)O)O.[Na+]
• Recent EU Clinical Trials: A Single-arm, Open Label Study Evaluating the Impact on Lifestyle of a New Thermo Stable Formulation of FLOLAN? in Subjects with Pulmonary Arterial Hypertension (PAH)
• Recent NIPH Clinical Trials: ACT-385781A PAH Post-marketing study
• Description: Epoprostenol is a naturally occurring prostaglandin indicated for the preservation of platelet function during cardiopulmonary bypass, prevention of platelet aggregation during charcoal hemoperfusion of patients in hepatic failure, and as an alternative to heparin during renal dialysis.
• Uses: Epoprostenol is an Eicosanoid which prevents the formation of platelet plugs and is an effective vasodilator. Prostaglandin I2 sodium salt has been used:in the preparation of stock solution for platelet washing procedureas supplement in platelet-rich-plasma, for platelet preparationto prevent platelet activation