Chlorodimethyloctadecylsilane

Base Information

• Chemical Name: Chlorodimethyloctadecylsilane
• CAS No.: 18643-08-8
• Deprecated CAS: 1247019-88-0,1690317-69-1
• Molecular Formula: C20H43ClSi
• Molecular Weight: 347.1
• Hs Code.: 29319090
• European Community (EC) Number: 242-472-2
• UNII: LH5E2W2ASN
• DSSTox Substance ID: DTXSID3066394
• Nikkaji Number: J149.983A
• Wikidata: Q72449541
• Mol file: 18643-08-8.mol

Synonyms:octadecyldimethylchlorosilane

Chemical Property of Chlorodimethyloctadecylsilane

Chemical Property:

• Appearance/Colour: white to off-white crystalline powder
• Vapor Pressure: 4.1E-06mmHg at 25°C
• Melting Point: 28-31 °C
• Refractive Index: 1.4530
• Boiling Point: 395.743 °C at 760 mmHg
• Flash Point: 209.593 °C
• PSA: 0.00000
• Density: 0.855 g/cm³
• LogP: 8.69180
• Sensitive.: Moisture Sensitive
• Water Solubility.: Reacts with water.
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 17
• Exact Mass: 346.2822556
• Heavy Atom Count: 22
• Complexity: 216

Purity/Quality:

99.9% ^*data from raw suppliers

Dimethyloctadecylchlorosilane >97.0%(T) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C,F
• Hazard Codes: C,F
• Statements: 34-67-65-63-48/20-11-10
• Safety Statements: 26-36/37/39-45-62

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCCCCCCCCCCCCCCCCC[Si](C)(C)Cl
• Uses: Chlorodimethyl-n-octadecylsilane is used for preparation of hydrophobic surfaces and chain terminator. Silylating reagent

Technology Process of Chlorodimethyloctadecylsilane

There total 7 articles about Chlorodimethyloctadecylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

dimethylmonochlorosilane (1066-35-9) + octadec-1-ene (112-88-9) → dimethyloctadecylchlorosilane (18643-08-8)

Guidance literature:

With platinum on carbon nanotubes; In neat (no solvent); at 20 ℃; for 24h;

DOI:10.1039/d0gc03943h

Reference yield: 98.0%

Hydroxydimethyloctadecylsilan (58626-12-3) → dimethyloctadecylchlorosilane (18643-08-8)

Guidance literature:

With thionyl chloride; N,N-dimethyl-formamide; In dichloromethane; at 20 ℃; for 24h; Temperature; Inert atmosphere;

DOI:10.1021/acs.orglett.6b00263

Reference yield: 87.0%

phosgene (75-44-5) + chloro-trimethyl-silane (75-77-4) + Hydroxydimethyloctadecylsilan (58626-12-3) + 1,2-dichloro-ethane (107-06-2,52399-93-6) → dimethyloctadecylchlorosilane (18643-08-8)

Guidance literature:

In N,N-dimethyl-formamide;

upstream raw materials:

dimethylsilicon dichloride

1-Bromooctadecane

dimethylmonochlorosilane

octadec-1-ene

Downstream raw materials:

(dimethylamino)dimethyl(octadecyl)silane

1-phenyl-2-(p-dimethyloctadecylsilyl)phenylacetylene

DMODS-melphalan

2-dimethyl-n-octylsilyl-5-dimethyl-n-octadecylsilyl-p-bis(bromomethyl)benzene

Refernces

• 1、 Hunnicutt, M. L.,Harris, J. M.. "Reactivity of Organosilane Reagents on Microparticulate Silica". . p. 748 - 752. Retrieved 1986.
• 2、 Naganawa, Yuki,Nakajima, Yumiko,Sakamoto, Kei. "A General and Selective Synthesis of Methylmonochlorosilanes from Di-, Tri-, and Tetrachlorosilanes". supporting information. p. 601 - 606. Retrieved 2021/01/13.
• 3、 Chao, Chih-Gang,Leibham, Ashley M.,Bergbreiter, David E.. "Hydrocarbon Soluble Recyclable Silylation Reagents and Purification Auxiliaries". supporting information. p. 1214 - 1216. Retrieved 2016/03/15.