3-Benzyl-2-oxo-hex-5-enoic acid allyl ester

Base Information

• Chemical Name: 3-Benzyl-2-oxo-hex-5-enoic acid allyl ester
• CAS No.: 125582-96-9
• Molecular Formula: C₁₆H₁₈O₃
• Molecular Weight: 258.317
• Mol file: 125582-96-9.mol

Synonyms:3-Benzyl-2-oxo-hex-5-enoic acid allyl ester

Chemical Property of 3-Benzyl-2-oxo-hex-5-enoic acid allyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 3-Benzyl-2-oxo-hex-5-enoic acid allyl ester

There total 3 articles about 3-Benzyl-2-oxo-hex-5-enoic acid allyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

allyl 3-allyloxycarbonyl-2-oxo-4-phenylbutanoate (125582-89-0) → 3-Benzyl-2-oxo-hex-5-enoic acid allyl ester (125582-96-9)

Guidance literature:

With triphenylphosphine; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; In tetrahydrofuran; at 65 ℃; for 3h;

Reference yield:

diallyl oxalate (615-99-6) → 3-Benzyl-2-oxo-hex-5-enoic acid allyl ester (125582-96-9)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium allyloxide / tetrahydrofuran / Ambient temperature

2: 83 percent / PPh₃ / Pd₂(DBA)3CHCl₃ / tetrahydrofuran / 3 h / 65 °C

With sodium allyloxide; triphenylphosphine; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; In tetrahydrofuran;

Reference yield:

allyl 3-phenylpropionate (15814-45-6) → 3-Benzyl-2-oxo-hex-5-enoic acid allyl ester (125582-96-9)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium allyloxide / tetrahydrofuran / Ambient temperature

2: 83 percent / PPh₃ / Pd₂(DBA)3CHCl₃ / tetrahydrofuran / 3 h / 65 °C

With sodium allyloxide; triphenylphosphine; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; In tetrahydrofuran;

upstream raw materials:

allyl 3-allyloxycarbonyl-2-oxo-4-phenylbutanoate

diallyl oxalate

allyl 3-phenylpropionate

Refernces