CYCLOPENTYLACETYLENE

Base Information

• Chemical Name: CYCLOPENTYLACETYLENE
• CAS No.: 930-51-8
• Molecular Formula: C7H10
• Molecular Weight: 94.1564
• Hs Code.: 29021990
• Mol file: 930-51-8.mol

Synonyms:Cyclopentylacetylene;Cyclopentylethyne; Ethynylcyclopentane

Chemical Property of CYCLOPENTYLACETYLENE

Chemical Property:

• Vapor Pressure: 46.8mmHg at 25°C
• Refractive Index: n20/D 1.432(lit.)
• Boiling Point: 98°Cat760mmHg
• Flash Point: °C
• PSA: 0.00000
• Density: 0.85g/cm³
• LogP: 1.80980
• Storage Temp.: Flammables area

Purity/Quality:

99% ^*data from raw suppliers

Cyclopentylacetylene ^*data from reagent suppliers

Safty Information:

• Hazard Codes: F,Xn
• Statements: 11-22
• Safety Statements: 16-7/9

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Cyclopentylacetylene is used as pharmaceutical intermediate.

Technology Process of CYCLOPENTYLACETYLENE

There total 10 articles about CYCLOPENTYLACETYLENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 26.0%

spiro<2.4>hept-1-ene (78578-84-4) → cyclopentylacetylene (930-51-8) + 1-vinylcyclopentene (28638-58-6) + 1,1-tetramethyleneallene (7439-00-1)

Guidance literature:

In pentane; Irradiation;

DOI:10.1039/c39830001504

Reference yield:

cyclopentanealdehyde (872-53-7) + dimethyl 1-(1-diazo-2-oxopropyl)phosphonate (90965-06-3) → cyclopentylacetylene (930-51-8)

Guidance literature:

With potassium carbonate; In methanol; diethyl ether; at 0 - 20 ℃; for 3h; Inert atmosphere;

DOI:10.1016/j.bmcl.2016.11.014

Reference yield:

cyclopentylethynyl-trimethyl-silane (205107-26-2) → cyclopentylacetylene (930-51-8)

Guidance literature:

With potassium carbonate; In methanol; at 20 ℃; for 3h; Inert atmosphere;

DOI:10.1021/ol503025n

upstream raw materials:

1-cyclopentylethanone

tricyclopentylborane

lithium acetylide-ethylenediamine complex

spiro<2.4>hept-1-ene

Downstream raw materials:

methyl 2-cyclopentylacrylate

methyl 3-cyclopentylacrylate

6-chloro-2-(2-cyclopentyl-1-ethynyl)-8-(3-fluorophenyl)-9-methyl-9H-purine

methyl 4-(cyclopropylethynyl)-2-(methylsulfonyl)benzoate

Refernces

• 1、 Dutta, Uttam,Maity, Soham,Kancherla, Rajesh,Maiti, Debabrata. "Aerobic oxynitration of alkynes with tBuONO and TEMPO". supporting information. p. 6302 - 6305. Retrieved 2015/02/19.
• 2、 Steinmetz, Mark G.,Yen, Yao-Pin,Poch, Gregory K.. "Comparison Between Ground and Excited State Reactivity of Cyclopropenes: Thermolysis and Far-U.v. (185 nm) Photolysis of Spirohept-1-ene". . p. 1504 - 1505. Retrieved 2007/10/02.