Ethyl 3-ethoxypropionate

Base Information

• Chemical Name: Ethyl 3-ethoxypropionate
• CAS No.: 763-69-9
• Deprecated CAS: 1391911-67-3
• Molecular Formula: C7H14O3
• Molecular Weight: 146.186
• Hs Code.: 2918990090
• European Community (EC) Number: 212-112-9
• NSC Number: 8870
• UN Number: 1993
• UNII: EC38RSJ79J
• DSSTox Substance ID: DTXSID0027309
• Nikkaji Number: J25.585H
• Wikidata: Q22829038
• ChEMBL ID: CHEMBL3561286
• Mol file: 763-69-9.mol

Synonyms:3-EEP;ethyl 3-ethoxypropionate

Chemical Property of Ethyl 3-ethoxypropionate

Chemical Property:

• Appearance/Colour: clear, colorless liquid
• Vapor Pressure: 1.8mmHg at 25°C
• Melting Point: -75 ºC
• Refractive Index: n20/D 1.405(lit.)
• Boiling Point: 166.2 ºC at 760 mmHg
• Flash Point: 52.2 ºC
• PSA: 35.53000
• Density: 0.949 g/cm³
• LogP: 0.97610
• Water Solubility.: 1.6 g/100 mL (20℃)
• XLogP3: 0.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• Exact Mass: 146.094294304
• Heavy Atom Count: 10
• Complexity: 90.9
• Transport DOT Label: Combustible Liquid

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s): Xi,N
• Hazard Codes: Xi:Irritant;; <
• Statements: R10:; R19:; R36:; R50:
• Safety Statements: S25:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Solvents -> Esters (
• Canonical SMILES: CCOCCC(=O)OCC

Technology Process of Ethyl 3-ethoxypropionate

There total 29 articles about Ethyl 3-ethoxypropionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

ethanol (64-17-5) + ethyl acrylate (140-88-5,9003-32-1) → ethyl 3-ethoxypropionate (763-69-9)

Guidance literature:

With quaternary ammonium salt anion exchange resin; In water; at 30 ℃; for 4h; Temperature; Inert atmosphere;

Reference yield: 97.6%

sodium ethanolate (141-52-6) + ethyl acrylate (140-88-5,9003-32-1) → ethyl 3-ethoxypropionate (763-69-9)

Guidance literature:

In ethanol; at 40 ℃; for 3h; Inert atmosphere;

Reference yield: 92.0%

formaldehyde diethyl acetal (462-95-3) → ethyl 3-ethoxypropionate (763-69-9)

Guidance literature:

With sulfuric acid; acetic anhydride;

upstream raw materials:

β-Propiolactone

ethanol

Ethyl 3-bromopropionate

sodium ethanolate

Downstream raw materials:

2-(2-ethoxy-ethyl)-1H-benzimidazole

3-ethoxy-1-propanol

2-aminopyrimidine-5-carboxylic acid ethyl ester

ethyl 2-chloropyrimidine-5-carboxylate

Refernces

• 1、 Cai, Zhenping,Chen, Rujia,Jiang, Lilong,Li, Fukun,Li, Xuehui,Long, Jinxing,Zhang, Hao. "One-pot production of diethyl maleate via catalytic conversion of raw lignocellulosic biomass". supporting information. p. 10116 - 10122. Retrieved 2021/12/24.
• 2、 -. "Method for producing Ethyl 3-Ethoxypropionate". Paragraph 0021. . Retrieved 2019/09/11.