3,3'-Diethyloxacarbocyanine iodide

Base Information

• Chemical Name: 3,3'-Diethyloxacarbocyanine iodide
• CAS No.: 905-96-4
• Molecular Formula: C₂₁H₂₁N₂O₂*I
• Molecular Weight: 460.314
• European Community (EC) Number: 212-996-6
• NSC Number: 96929
• ChEMBL ID: CHEMBL79003
• Mol file: 905-96-4.mol

Synonyms:3,3'-diethyloxacarbocyanine;3,3'-diethyloxacarbocyanine iodide;DiOC2;DiOC2(3)

Chemical Property of 3,3'-Diethyloxacarbocyanine iodide

Chemical Property:

• Melting Point: 278 °C (dec.)(lit.)
• PSA: 35.09000
• LogP: 1.08680
• Sensitive.: Light Sensitive
• Solubility.: Soluble in methanol, dimethyl sulfoxide
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 460.06478
• Heavy Atom Count: 26
• Complexity: 474

Purity/Quality:

98%,99%, ^*data from raw suppliers

3,3'-Diethyloxacarbocyanine Iodide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCN1C2=CC=CC=C2OC1=CC=CC3=[N+](C4=CC=CC=C4O3)CC.[I-]
• Isomeric SMILES: CCN\1C2=CC=CC=C2O/C1=C\C=C\C3=[N+](C4=CC=CC=C4O3)CC.[I-]
• Uses: 3,3''-Diethyloxacarbocyanine Iodide is a fluorescent probe for measuring membrane potential. It has been used to analyze bacterial viability by flow cytometry using fluorescence emission ratio detection. DiOC may be used as a conjugate for labelling cells for cytofluorometry studies . It may also be used in the imaging of carbon nanotubes(CNTs) using fluorescence microscopy. Staining of spermatozoa can potentially be done by DiOC which can be used in flow cytometric measurement and viability assay.

Technology Process of 3,3'-Diethyloxacarbocyanine iodide

There total 5 articles about 3,3'-Diethyloxacarbocyanine iodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

orthoformic acid triethyl ester (122-51-0) → 3,3'-diethyloxacarbocyanine iodide (905-96-4,57441-52-8,57441-62-0,149436-28-2)

Guidance literature:

With pyridine;

Reference yield:

aniline (62-53-3) → 3,3'-diethyloxacarbocyanine iodide (905-96-4,57441-52-8,57441-62-0,149436-28-2)

Guidance literature:

With acetone;

Reference yield:

diethoxymethyl acetate (14036-06-7) + 3-ethyl-2-methyl-1,3-benzoxazol-3-ium iodide (5260-37-7) → 3,3'-diethyloxacarbocyanine iodide (905-96-4,57441-52-8,57441-62-0,149436-28-2)

Guidance literature:

upstream raw materials:

diethoxymethyl acetate

3-ethyl-2-methyl-1,3-benzoxazol-3-ium iodide

Vilsmeier reagent

orthoformic acid triethyl ester

Refernces