flaviolin

Base Information

• Chemical Name: flaviolin
• CAS No.: 479-05-0
• Molecular Formula: C10H6 O5
• Molecular Weight: 206.155
• Mol file: 479-05-0.mol

Synonyms:1,4-Naphthoquinone,2,5,7-trihydroxy- (6CI,7CI,8CI); 2,5,7-Trihydroxy-1,4-naphthoquinone; Flaviolin

Chemical Property of flaviolin

Chemical Property:

• Vapor Pressure: 3.01E-12mmHg at 25°C
• Melting Point: 250 °C (approx, decomp)(Solv: 1,4-dioxane (123-91-1))
• Boiling Point: 539.4°Cat760mmHg
• PKA: 4.50±1.00(Predicted)
• Flash Point: 294.1°C
• PSA: 94.83000
• Density: 1.802g/cm³
• LogP: 0.76210

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of flaviolin

There total 20 articles about flaviolin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

1,3,6,8-Tetrahydroxynaphthalene (18512-30-6) → flaviolin (479-05-0)

Guidance literature:

With oxygen; potassium carbonate; In N,N-dimethyl-formamide; at 25 ℃; for 10h;

Reference yield: 25.0%

1,3,6,8-Tetrahydroxynaphthalene (18512-30-6) → 3,6,8-Trihydroxy-3,4-dihydronaphthalen-1(2H)-one (49598-85-8,59872-10-5,144068-45-1) + flaviolin (479-05-0)

Guidance literature:

With sodium tetrahydroborate; sodium methylate; In methanol; Mechanism;

Reference yield: 20.0%

1,3,6,8-Tetrahydroxynaphthalene (18512-30-6) → 3,6,8-Trihydroxy-3,4-dihydronaphthalen-1(2H)-one (49598-85-8,59872-10-5,144068-45-1) + flaviolin (479-05-0) + 6,8-dihydroxy-1-methylisochroman-3-one (77053-29-3)

Guidance literature:

With sodium tetrahydroborate; In methanol;

upstream raw materials:

1,3,6,8-Tetrahydroxynaphthalene

5-hydroxy-2,7-dimethoxy-1,4-naphthoquinone

5,7-dihydroxy-1,4-naphthoquinone

scytalone

Downstream raw materials:

5-hydroxy-2,7-dimethoxy-1,4-naphthoquinone

Refernces

• 1、 Vagstad, Anna L.,Hill, Eric A.,Labonte, Jason W.,Townsend, Craig A.. "Characterization of a fungal thioesterase having claisen cyclase and deacetylase activities in melanin biosynthesis". . p. 1525 - 1534. Retrieved 2013/02/25.
• 2、 Jeong, Jae-Cheol,Srinivasan, Aravind,Grueschow, Sabine,Bach, Horacio,Sherman, David H.,Dordick, Jonathan S.. "Exploiting the reaction flexibility of a type III polyketide synthase through in vitro pathway manipulation". . p. 64 - 65. Retrieved 2007/10/03.