Technology Process of C38H52N8O9S
There total 21 articles about C38H52N8O9S which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
acetic acid; N-ethyl-N,N-diisopropylamine;
In
N,N-dimethyl-formamide;
at 50 ℃;
for 2h;
DOI:10.1021/ja00087a007
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 99.5 percent / HBTU, DIEA / CH2Cl2 / 1 h
2: 86.2 percent / TFA / 0.08 h
3: HBTU, DIEA / CH2Cl2 / a) 0 deg C, 15 min, b) RT, 2 d
4: H2 / 10percent Pd/C / methanol
5: HBTU, DIEA / dimethylformamide / 4 h
6: CH2Cl2 / 0.75 h
7: DIEA, AcOH / dimethylformamide / 2 h / 50 °C
With
hydrogen; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; acetic acid; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid;
palladium on activated charcoal;
In
methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ja00087a007
- Guidance literature:
-
Multi-step reaction with 5 steps
1: HBTU, DIEA / CH2Cl2 / a) 0 deg C, 15 min, b) RT, 2 d
2: H2 / 10percent Pd/C / methanol
3: HBTU, DIEA / dimethylformamide / 4 h
4: CH2Cl2 / 0.75 h
5: DIEA, AcOH / dimethylformamide / 2 h / 50 °C
With
hydrogen; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; acetic acid; N-ethyl-N,N-diisopropylamine;
palladium on activated charcoal;
In
methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ja00087a007
