Esbuphon

Base Information Edit

Chemical Name:Esbuphon
CAS No.:4779-94-6
Deprecated CAS:15308-34-6
Molecular Formula:C8H11 N O2 . Cl H
Molecular Weight:189.642
Hs Code.:2922504500
European Community (EC) Number:239-351-1
NCI Thesaurus Code:C81364
Mol file:4779-94-6.mol

Synonyms:Esbuphon;Zondel;Novadral;m-Octopamine hydrochloride;UNII-1FCN9TAU6R;Norphenephrine hydrochloride;DL-m-Octopamine hydrochloride;Molycor-R hydrochloride;WIN 5501;(+-)-Norphenylephrine hydrochloride;EINECS 225-323-6;EINECS 239-351-1;NSC 100733;NSC 297582;Norfenefrine dl-form hydrochloride;DL-Aminomethyl-3-hydroxybenzyl alcohol hydrochloride;[2-hydroxy-2-(3-hydroxyphenyl)ethyl]azanium;chloride;alpha-Aminomethyl-3-hydroxybenzyl alcohol hydrochloride;Norfenefrine dl-form HCl;1FCN9TAU6R;(+-)-alpha-(Aminomethyl)-m-hydroxybenzyl alcohol hydrochloride;Benzenemethanol, alpha-(aminomethyl)-3-hydroxy-, hydrochloride;BENZYL ALCOHOL, alpha-AMINOMETHYL-3-HYDROXY-, HYDROCHLORIDE;Benzenemethanol, .alpha.-(aminomethyl)-3-hydroxy-, hydrochloride, (.+.)-;Benzenemethanol, alpha-(aminomethyl)-3-hydroxy-, hydrochloride, (+)-;15308-34-6;AKOS015907963;LS-42693;LS-42695;rac Norphenylephrine Hydrochloride(Phenylephrine Impurity A);Benzenemethanol, alpha-(aminomethyl)-3-hydroxy-, hydrochloride, (+-)-;BENZYL ALCOHOL, alpha-(AMINOMETHYL)-m-HYDROXY-, HYDROCHLORIDE, (+-)-

Suppliers and Price of Esbuphon

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
racNorphenylephrineHydrochloride(PhenylephrineImpurityA)
250mg
$ 425.00

Sigma-Aldrich
Norphenylephrine hydrochloride United States Pharmacopeia (USP) Reference Standard
25mg
$ 1260.00

Sigma-Aldrich
Norphenylephrine Hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material
200mg
$ 130.00

Sigma-Aldrich
Norphenylephrine hydrochloride 98%
10g
$ 77.90

Matrix Scientific
3-(2-Amino-1-hydroxyethyl)phenol
500mg
$ 76.00

Chem-Impex
Norphenylephrinehydrochloride,98%(AT) 98%(AT)
5G
$ 22.40

Chem-Impex
Norphenylephrinehydrochloride,≥98%(AT) ≥98%(AT)
25G
$ 81.54

Chem-Impex
Norphenylephrinehydrochloride,≥98%(AT) ≥98%(AT)
100G
$ 262.08

Biosynth Carbosynth
rac-Norphenylephrine hydrochloride
100 g
$ 500.00

Biosynth Carbosynth
rac-Norphenylephrine hydrochloride
50 g
$ 400.00

Total 36 raw suppliers

Chemical Property of Esbuphon Edit

Chemical Property:

Melting Point:162-164 °C(lit.)
Boiling Point:360.7°Cat760mmHg
Flash Point:172°C
PSA：66.48000
Density:1.249g/cm³
LogP:1.88660
Storage Temp.:-20°C Freezer, Under Inert Atmosphere
Solubility.:DMSO (Slightly), Methanol (Slightly), Water (Slightly)
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:189.0556563
Heavy Atom Count:12
Complexity:119

Purity/Quality:

98%,99%, ^*data from raw suppliers

racNorphenylephrineHydrochloride(PhenylephrineImpurityA) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=CC(=CC(=C1)O)C(C[NH3+])O.[Cl-]
Uses rac Norphenylephrine Hydrochloride is an Impurity A of phenylephrine. A phenylephrine derivative as leukotriene D4 antagonists. Impurity A of phenylephrine. A phenylephrine derivative as leukotriene D4 antagonists.
Therapeutic Function Adrenergic

Technology Process of Esbuphon

There total 3 articles about Esbuphon which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.3%