3,3'-dimethylbenzoin

Base Information

• Chemical Name: 3,3'-dimethylbenzoin
• CAS No.: 1218-85-5
• Molecular Formula: C₁₆H₁₆O₂
• Molecular Weight: 240.302
• Mol file: 1218-85-5.mol

Synonyms:3,3'-dimethylbenzoin

Chemical Property of 3,3'-dimethylbenzoin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,3'-dimethylbenzoin

There total 3 articles about 3,3'-dimethylbenzoin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

m-tolyl aldehyde (620-23-5) → 3,3'-dimethylbenzoin (1218-85-5)

Guidance literature:

With potassium cyanide; In dimethyl sulfoxide; for 0.333333h; Inert atmosphere; Sonication;

Reference yield: 56.0%

acrylic acid methyl ester (292638-85-8,9003-21-8,96-33-3) + m-tolyl aldehyde (620-23-5) → 5-(3-methylbenzoyl)-5-(3-methylphenyl)-tetrahydro-2(3H)-furanone + 3,3'-dimethylbenzoin (1218-85-5)

Guidance literature:

m-tolyl aldehyde; With potassium tert-butylate; 1,3-dimethylimidazolim iodide; In tetrahydrofuran; at 20 ℃; for 3h;

acrylic acid methyl ester; In tetrahydrofuran; at 20 ℃; for 8h;

DOI:10.1021/ol051422m

Reference yield:

→ 3,3'-dimethylbenzoin (1218-85-5)

Guidance literature:

aus m-Methylphenyllithium u. Ni(CO)4 in Ether bei -70grad;

upstream raw materials:

m-tolyl aldehyde

acrylic acid methyl ester

Downstream raw materials:

4,5-Di-m-tolyl-1,3-dihydro-imidazole-2-thione

4,5-bis-(3-methylphenyl)-5H-[1,2,3]oxathiazole 2,2-dioxide

(4S,5R)-4,5-bis-(3-methylphenyl)-[1,2,3]oxathiazolidine 2,2-dioxide

2,3-Bis(3-methylphenyl)chinoxalin

Refernces

• 1、 Onida, Killian,Haddleton, Alice J.,Norsic, Sébastien,Boisson, Christophe,D'Agosto, Franck,Duguet, Nicolas. "Organocatalytic Synthesis of Substituted Vinylene Carbonates". supporting information. p. 5129 - 5137. Retrieved 2021/09/18.
• 2、 Qian, Cunwei,Yao, Changsheng,Yang, Liujun,Yang, Bo,Liu, Shuchun,Liu, Zongtang. "Preparation and Application of Silica Films Supported Imidazolium-Based Ionic Liquid as Efficient and Recyclable Catalysts for Benzoin Condensations". . p. 1389 - 1396. Retrieved 2019/11/21.