CID 10329024

Base Information

• Chemical Name: CID 10329024
• CAS No.: 7240-37-1
• Molecular Formula: C62H87 N13 O16
• Molecular Weight: 1270.4317
• Hs Code.: 29419090
• European Community (EC) Number: 635-285-6
• Wikipedia: 7-Aminoactinomycin_D
• NCI Thesaurus Code: C72904
• Mol file: 7240-37-1.mol

Synonyms:7-AAD;7-ADD;7-amino-actinomycin D;7-aminoactinomycin D

Chemical Property of CID 10329024

Chemical Property:

• Appearance/Colour: RED TO DARK PURPLE POWDER
• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 252～253℃
• Boiling Point: 1400.8 °C at 760 mmHg
• PKA: 8.90±0.70(Predicted)
• Flash Point: 801 °C
• PSA: 386.00000
• Density: 1.44 g/cm³
• LogP: 2.53700
• Storage Temp.: 2-8°C
• Solubility.: chloroform: 1 mg/mL, clear, red
• XLogP3: 3.1
• Hydrogen Bond Donor Count: 6
• Hydrogen Bond Acceptor Count: 19
• Rotatable Bond Count: 8
• Exact Mass: 1269.63937374
• Heavy Atom Count: 91
• Complexity: 3070

Purity/Quality:

98%,99%, ^*data from raw suppliers

7-Aminoactinomycin D ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T+
• Hazard Codes: T+,T
• Statements: 26/27/28-36/37/38
• Safety Statements: 26-28-36/37-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC1C(C(=O)NC(C(=O)N2CCCC2C(=O)N(CC(=O)N(C(C(=O)O1)C(C)C)C)C)C(C)C)NC(=O)C3=CC(=C(C4=C3N=C5C(=C(C(=O)C(=C5O4)C)N)C(=O)NC6C(OC(=O)C(N(C(=O)CN(C(=O)C7CCCN7C(=O)C(NC6=O)C(C)C)C)C)C(C)C)C)C)N
• Isomeric SMILES: C[C@@H]1[C@@H](C(=O)N[C@H](C(=O)N2CCC[C@H]2C(=O)N(CC(=O)N([C@H](C(=O)O1)C(C)C)C)C)C(C)C)NC(=O)C3=CC(=C(C4=C3N=C5C(=C(C(=O)C(=C5O4)C)N)C(=O)N[C@H]6[C@H](OC(=O)[C@@H](N(C(=O)CN(C(=O)[C@@H]7CCCN7C(=O)[C@@H](NC6=O)C(C)C)C)C)C(C)C)C)C)N
• Description: 7-Aminoactinomycin D (7-AAD) is a fluorescent DNA dye that is commonly used for the detection or exclusion of non-viable cells in flow cytometric analysis, as it is generally excluded by live cells. It displays excitation spectra of 488, 546, and 578 nm and an emission spectrum of 650 nm. As 7-AAD is detected in the far red range of the spectrum, it exhibits minimal spectral overlap with commonly used probes, therefore it can be used in conjunction with probes such as FITC. 7-AAD has been used to evaluate apoptosis and cell-mediated cytotoxicity and to stain DNA in cells that have been fixed and permeabilized by a variety of methods.
• Uses: Fluorescent DNA stain. A featured product for Apoptosis research. 7-Aminoactinomycin D is a fluorescent DNA dye for apoptosis and flow cytomtery studies.