Kauniolide

Base Information

• Chemical Name: Kauniolide
• CAS No.: 81066-45-7
• Molecular Formula: C15H18O2
• Molecular Weight: 230.307
• Mol file: 81066-45-7.mol

Synonyms:Kauniolide;

Chemical Property of Kauniolide

Chemical Property:

• PSA: 26.30000
• LogP: 3.16070

Purity/Quality:

≥98% ^*data from raw suppliers

Kauniolide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Kauniolide is a sesquiterpene lactone with potential for inhibition towards glucose induced NF-kB activation involved in diabetic neuropathy. As well, sesquiterpene lactones maybe be used as cytotoxic agents.

Technology Process of Kauniolide

There total 1 articles about Kauniolide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dehydrocostus lactone (74299-48-2,93219-83-1,477-43-0) → kauniolide (81066-45-7)

Guidance literature:

With silica gel; for 0.1h; microwave irradiation;

Reference yield: 27.1%

kauniolide (81066-45-7) → C15H18O3 (137624-14-7) + C15H18O3 (157751-04-7) + 1β,10β-Epoxyguaia-3,11(13)-dien-12,6α-olide (137624-14-7,84692-91-1)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 20 ℃;

DOI:10.1021/jo300888s

upstream raw materials:

dehydrocostus lactone

Downstream raw materials:

C₁₅H₁₈O₃

C₁₅H₁₈O₃

1β,10β-Epoxyguaia-3,11(13)-dien-12,6α-olide

Refernces