Technology Process of (E)-2-nitro-4-(4-nitrostyryl)phenol
There total 4 articles about (E)-2-nitro-4-(4-nitrostyryl)phenol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium acetate; palladium diacetate;
In
methanol;
at 20 ℃;
for 12h;
Inert atmosphere;
DOI:10.1039/c3ob40420j
- Guidance literature:
-
N-(4-hydroxy-3-nitrophenyl)acetamide;
With
boron trifluoride methanol complex;
In
methanol;
at 65 ℃;
Inert atmosphere;
With
tert.-butylnitrite;
In
methanol;
at 0 ℃;
for 1h;
Inert atmosphere;
4-nitrostyrene;
With
palladium diacetate;
In
methanol;
at 20 ℃;
for 12.25h;
Inert atmosphere;
DOI:10.1002/adsc.201200929
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: potassium carbonate / tetrahydrofuran / 6 h / Inert atmosphere; Reflux
2.1: boron trifluoride methanol complex / methanol / 65 °C / Inert atmosphere
2.2: 1 h / 0 °C / Inert atmosphere
2.3: 12.25 h / 20 °C / Inert atmosphere
With
boron trifluoride methanol complex; potassium carbonate;
In
tetrahydrofuran; methanol;
1.1: |Wittig Olefination / 2.3: |Heck Reaction;
DOI:10.1002/adsc.201200929
