C₄₂H₃₉N₃O₃

Base Information

• Chemical Name: C₄₂H₃₉N₃O₃
• CAS No.: 945267-56-1
• Molecular Formula: C₄₂H₃₉N₃O₃
• Molecular Weight: 633.79
• Mol file: 945267-56-1.mol

Synonyms:C₄₂H₃₉N₃O₃

Chemical Property of C₄₂H₃₉N₃O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₂H₃₉N₃O₃

There total 3 articles about C₄₂H₃₉N₃O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

5-(bromomethyl)-2-phenylpyridine (212573-56-3) + cis,cis-1,3,5-trihydroxycyclohexane (50409-12-6,13314-30-2) → C42H39N3O3 (945267-56-1)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 24h; Inert atmosphere;

DOI:10.1039/c2dt12309f

Reference yield:

5-methyl-2-phenylpyridine (27012-22-2) → C42H39N3O3 (945267-56-1)

Guidance literature:

Multi-step reaction with 2 steps

1: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane / 3 h / Reflux

2: sodium hydride / N,N-dimethyl-formamide / 24 h / 20 °C / Inert atmosphere

With N-Bromosuccinimide; sodium hydride; dibenzoyl peroxide; In tetrachloromethane; N,N-dimethyl-formamide;

DOI:10.1039/c2dt12309f

Reference yield:

phenylboronic acid (98-80-6) → C42H39N3O3 (945267-56-1)

Guidance literature:

Multi-step reaction with 3 steps

1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate / ethanol; water; toluene / 48 h / Inert atmosphere; Reflux

2: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane / 3 h / Reflux

3: sodium hydride / N,N-dimethyl-formamide / 24 h / 20 °C / Inert atmosphere

With N-Bromosuccinimide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium hydride; potassium carbonate; dibenzoyl peroxide; In tetrachloromethane; ethanol; water; N,N-dimethyl-formamide; toluene;

DOI:10.1039/c2dt12309f

upstream raw materials:

5-(bromomethyl)-2-phenylpyridine

cis,cis-1,3,5-trihydroxycyclohexane

5-methyl-2-phenylpyridine

phenylboronic acid

Refernces