Chloromercuribenzoate

Base Information

• Chemical Name: Chloromercuribenzoate
• CAS No.: 59-85-8
• Deprecated CAS: 107296-30-0,130973-93-2,136969-76-1,139116-12-4,145757-52-4,172906-39-7,75344-65-9,77329-67-0,92421-68-6,792952-75-1,1356399-46-6,856770-63-3,1416052-38-4,2101845-36-5,2417134-16-6
• Molecular Formula: C7H4 Cl Hg O2 . H
• Molecular Weight: 357.159
• UNII: E1LE0WZ4BO
• Mol file: 59-85-8.mol

Synonyms:Chloromercuribenzoate;Chloromercuribenzoic acid;NSC 32866;E1LE0WZ4BO;p-Chloro-mercuric benzoic acid;Benzoic acid, p-(chloromercuri)-;EINECS 200-442-6;AI3-15315;(4-Carboxylatophenyl)chloromercurate(1-), hydrogen;UNII-E1LE0WZ4BO;LS-89688

Chemical Property of Chloromercuribenzoate

Chemical Property:

• Appearance/Colour: White Solid
• Melting Point: 287 °C (dec.)(lit.)
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 37.30000
• Density: g/cm³
• LogP: 1.24640
• Storage Temp.: -20?C Freezer
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 357.968451
• Heavy Atom Count: 11
• Complexity: 128

Purity/Quality:

98%min ^*data from raw suppliers

4-Chloromercuribenzoic acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T+,N
• Hazard Codes: T+,N
• Statements: 26/27/28-33-50/53
• Safety Statements: 13-28-36-45-60-61

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC(=CC=C1C(=O)O)[Hg+].[Cl-]
• Uses: 4-CHLOROMERCURIBENZOIC ACID can be used to inhibit some enzymes that require unmodified cysteine residues (e.g., adenylyl cyclase). A useful sulfhydryl reagent that reacts with Histidine 225C, a residue of the NhaA-Na/H Antiporter of Escherichia Coli Can be used to inhibit some enzymes that require unmodified cysteine residues (e.g., adenylyl cyclase).

Technology Process of Chloromercuribenzoate

There total 1 articles about Chloromercuribenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ p-chloromercuribenzoic acid (59-85-8)

Guidance literature:

With potassium permanganate;

Reference yield: 70.0%

p-chloromercuribenzoic acid (59-85-8) + diphenylcarbazone (538-62-5) → C6H4(COOH)Hg[C6H5NNCONNHC6H5]

Guidance literature:

With perchlorate buffer; In tetrachloromethane; water; a soln. of the arylmercuric chloride in perchlorate buffer (pH 7) is shaken with a soln. of diphenylcarbazone in CCl4 for 20 min; the organic layer is separated, the solvent is evapd. under reduced pressure, the residue is washed, elem. anal.;

Reference yield:

norborn-2-ene (498-66-8) + p-chloromercuribenzoic acid (59-85-8) → 7-(p-Carboxy-phenyl)-2-chlor-bicyclo<2.2.1>-heptan (20849-76-7)

Guidance literature:

With lithium chloride; copper dichloride; lithium tetrachloropalladate(II); In acetic acid;

DOI:10.1021/ja01022a038

Downstream raw materials:

1-(4-methoxycarbonylphenyl)-2-phenylethene

p-Methoxycarboxy-zimtsaeuremethylester

7-(p-Carboxy-phenyl)-2-chlor-bicyclo<2.2.1>-heptan

4-(2-chloro-3-oxo-butyl)-benzoic acid