Technology Process of 2-Benzyl-1,2,3,4,4a,9-hexahydro-trans-13bH-9,13b-methanodibenzo<3,4;6,7>cyclohepta<1,2-c>pyridine
There total 5 articles about 2-Benzyl-1,2,3,4,4a,9-hexahydro-trans-13bH-9,13b-methanodibenzo<3,4;6,7>cyclohepta<1,2-c>pyridine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
potassium tert-butylate;
In
dimethyl sulfoxide;
at 100 ℃;
for 60h;
Yield given;
DOI:10.1021/jo01296a032
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1.) THF, pyridine, RT, 3 h, 2.) p-xylene, reflux, 90 min
2: 30.5 percent / p-Toluenesulfonic acid / acetic acid / 26 h / Heating
3: 10percent Pd/C, H2 / tetrahydrofuran; acetic acid / 84 h / 2585.7 Torr / Parr shaker
4: 63 percent / LiAlH4 / tetrahydrofuran / 4 h / Heating
5: Potassium tert-butoxide / dimethylsulfoxide / 60 h / 100 °C
With
palladium on activated charcoal; lithium aluminium tetrahydride; potassium tert-butylate; hydrogen; toluene-4-sulfonic acid;
In
tetrahydrofuran; acetic acid; dimethyl sulfoxide;
DOI:10.1021/jo01296a032
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 10percent Pd/C, H2 / tetrahydrofuran; acetic acid / 84 h / 2585.7 Torr / Parr shaker
2: 63 percent / LiAlH4 / tetrahydrofuran / 4 h / Heating
3: Potassium tert-butoxide / dimethylsulfoxide / 60 h / 100 °C
With
palladium on activated charcoal; lithium aluminium tetrahydride; potassium tert-butylate; hydrogen;
In
tetrahydrofuran; acetic acid; dimethyl sulfoxide;
DOI:10.1021/jo01296a032