DIOXOLANE418

Base Information

• Chemical Name: DIOXOLANE418
• CAS No.: 60644-92-0
• Molecular Formula: C5Cl2F8O2
• Molecular Weight: 314.947
• Hs Code.: 2932999099
• Mol file: 60644-92-0.mol

Synonyms:4,5-Dichloro-4,5-difluoro-2,2-bis(trifluoromethyl)-1,3-dioxolane;Perfluoro-2,2-dimethyl-4,5-dichloro-1,3-dioxolane;

Chemical Property of DIOXOLANE418

Chemical Property:

• Vapor Pressure: 17.1mmHg at 25°C
• Refractive Index: 1.352
• Boiling Point: 121.9 °C at 760 mmHg
• Flash Point: 27.5 °C
• PSA: 18.46000
• Density: 1.82 g/cm³
• LogP: 3.57830

Purity/Quality:

99% ^*data from raw suppliers

2,2-Bis(trifluoromethyl)-4,5-dichloro-4,5-difluoro-1,3-dioxolane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of DIOXOLANE418

There total 6 articles about DIOXOLANE418 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

2,2-bis(trifluoromethyl)-4,4,5,5-tetrachloro-1,3-dioxacyclopentane (64499-81-6) → 2,2-bis(trifluoromethyl)-4,5-dichloro-4,5-difluoro-1,3-dioxolane (60644-92-0)

Guidance literature:

With hydrogen trifluoride triethylamine salt; triethylamine; In acetonitrile; at 100 ℃; for 8h;

Reference yield: 65.0%

2,2-bis(trifluoromethyl)-4,4,5,5-tetrachloro-1,3-dioxacyclopentane (64499-81-6) → 2,2-bis(trifluoromethyl)-4,5-dichloro-4,5-difluoro-1,3-dioxolane (60644-92-0) + 2,2-bis(trifluoromethyl)-4-chloro-4,5,5-trifluoro-1,3-dioxolane (135014-05-0)

Guidance literature:

With antimonypentachloride; antimony(III) fluoride; titanium tetrachloride; a) 70 deg C, 1 h, b) 180 deg C, 8 h;

Reference yield: 11.5%

1,2-dichloro-1,2-difluoroethene (598-88-9) + Hexafluoroacetone (684-16-2) → 2,2-bis(trifluoromethyl)-4,5-dichloro-4,5-difluoro-1,3-dioxolane (60644-92-0)

Guidance literature:

Hexafluoroacetone; With C₅Cl₃F₉O; cesium fluoride; In water; at 20 ℃; for 12h;

With fluorine; In water; at -78 ℃; for 4.7h; Inert atmosphere;

1,2-dichloro-1,2-difluoroethene; In water; at -78 ℃; for 1h; Reagent/catalyst; Temperature; Inert atmosphere;

upstream raw materials:

2,2-bis(trifluoromethyl)-4,4,5,5-tetrachloro-1,3-dioxacyclopentane

2,2-bis(trifluoromethyl)-1,3-dioxolane

1,2-dichloro-1,2-difluoroethene

Hexafluoroacetone

Downstream raw materials:

4,5-Difluoro-2,2-bis(trifluoromethyl)-1,3-dioxole

Refernces

• 1、 -. "PRODUCTION METHODS FOR 1,3-DIOXOLANE COMPOUND AND PERFLUORO(2,2-DIMETHYL-1,3-DIOXOLE)". Paragraph 0079-0086; 0088-0092. . Retrieved 2020/12/03.