Carboxymethoxylamine hemihydrochloride

Base Information

• Chemical Name: Carboxymethoxylamine hemihydrochloride
• CAS No.: 2921-14-4
• Molecular Formula: 2C₂H₅NO₃*ClH
• Molecular Weight: 218.594
• Hs Code.: 29280000
• NSC Number: 56446,50782,40358
• ChEMBL ID: CHEMBL1255757
• Mol file: 2921-14-4.mol

Synonyms:Aceticacid, (aminooxy)-, hemihydrochloride (6CI);Acetic acid, (aminooxy)-,hydrochloride (2:1) (8CI,9CI);Aminooxyacetic acid hemichloride;Aminooxyaceticacid hemihydrochloride;Carboxymethoxyamine hemihydrochloride;O-Carboxymethylhydroxylaminehemihydrochloride;

Chemical Property of Carboxymethoxylamine hemihydrochloride

Chemical Property:

• Appearance/Colour: white to off-white crystalline powder or crystals
• Vapor Pressure: 4.24E-05mmHg at 25°C
• Melting Point: 156 °C (dec.)(lit.)
• Refractive Index: 1.6500 (estimate)
• Boiling Point: 326.7 °C at 760 mmHg
• Flash Point: 151.4 °C
• PSA: 145.10000
• Density: 1.7848 (rough estimate)
• LogP: 0.12520
• Storage Temp.: -20°C Freezer
• Water Solubility.: decomposes
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 127.0036207
• Heavy Atom Count: 7
• Complexity: 52.8

Purity/Quality:

98%,99%, ^*data from raw suppliers

CarboxymethoxyamineHemihydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C(C(=O)O)ON.Cl
• Uses: Undergoes condensation with aldehydes and ketones to form oximes. A bifunctional linking reagent

Technology Process of Carboxymethoxylamine hemihydrochloride

There total 5 articles about Carboxymethoxylamine hemihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C2H3NO9S2(2-)*2Na(1+) → (aminooxy)acetic acid hemihydrochloride (2921-14-4,7776-18-3,20295-82-3)

Guidance literature:

C₂H₃NO₉S₂^(2-)*2Na⁽¹⁺⁾; With sulfuric acid; In water; at 90 ℃; for 24h;

With hydrogenchloride; In water;

Reference yield:

[(propan-2-ylideneamino)oxy]acetic acid (5382-89-8) → (aminooxy)acetic acid hemihydrochloride (2921-14-4,7776-18-3,20295-82-3)

Guidance literature:

With hydrogenchloride; water;

DOI:10.1021/ja01185a513 DOI:10.1021/ja01301a058

Reference yield:

→ (aminooxy)acetic acid hemihydrochloride (2921-14-4,7776-18-3,20295-82-3)

Guidance literature:

With hydrogenchloride; at 100 ℃;

upstream raw materials:

[(propan-2-ylideneamino)oxy]acetic acid

Downstream raw materials:

(6R)-3-(carboxymethoxyimino-methyl)-8-oxo-7t-(2-thiophen-2-yl-acetylamino)-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester

ethyl 2-(aminooxy)-acetate

<2-Phenyl-cyclopentylidenaminooxy>-essigsaeure

Acetaminooxyessigsaeure

Refernces

• 1、 -. "Aminooxyamide tricyclic inhibitors of farnesyl-protein transferase". . . Retrieved 2008/06/13.