Succinimide, thio-

Base Information

• Chemical Name: Succinimide, thio-
• CAS No.: 4166-00-1
• Molecular Formula: C₄H₅NOS
• Molecular Weight: 115.156
• Hs Code.: 2933790090
• DSSTox Substance ID: DTXSID10194484
• Nikkaji Number: J48.682E
• Mol file: 4166-00-1.mol

Synonyms:Succinimide, thio-;5-Thioxopyrrolidin-2-one;Monothiosuccinimide;Thiosuccinimide;4166-00-1;5-sulfanylidenepyrrolidin-2-one;USAF WI-1;2-Thiosuccinimide;2-Pyrrolidinone, 5-thioxo-;BRN 1524377;5-Thioxo-2-pyrrolidinone #;SCHEMBL407973;DTXSID10194484;WJQDJDVDXAAXSB-UHFFFAOYSA-N;AKOS032971354;LS-147646;N13285

Chemical Property of Succinimide, thio-

Chemical Property:

• Melting Point: 113°C
• Refractive Index: 1.5130 (estimate)
• Boiling Point: 110°C
• PSA: 64.68000
• Density: 1.33g/cm³
• LogP: 0.49970
• XLogP3: -0.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 115.00918496
• Heavy Atom Count: 7
• Complexity: 121

Purity/Quality:

99%, ^*data from raw suppliers

THIOSUCCINIMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC(=S)NC1=O

Technology Process of Succinimide, thio-

There total 4 articles about Succinimide, thio- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

Succinimide (123-56-8,89963-74-6) → monothiosuccinimide (4166-00-1)

Guidance literature:

With 2,4-bis(methylthio)-1,3-dithia-2,4-diphosphetane-2,4-disulfide; In 1,2-dimethoxyethane; 60 min 20 deg C, 30 min 60 deg C;

DOI:10.1016/S0040-4020(01)88445-3

Reference yield: 26.0%

Succinimide (123-56-8,89963-74-6) → monothiosuccinimide (4166-00-1) + dithio-succinimide (13070-03-6)

Guidance literature:

With 2,4-(4-phenoxyphenyl)-1,3-dithia-2λ(5),4λ(5)-diphosphetane 2,4-disulfides; In 1,2-dimethoxyethane; at 60 ℃; for 2h;

DOI:10.1016/S0040-4020(01)88445-3

Reference yield: 18.0%

1-Phenethyl-5-thioxo-pyrrolidin-2-one (147767-13-3) → monothiosuccinimide (4166-00-1)

Guidance literature:

In benzene; for 5h; Ambient temperature; Irradiation;

DOI:10.3987/COM-92-6141

upstream raw materials:

Succinimide

1-Phenethyl-5-thioxo-pyrrolidin-2-one

Refernces

• 1、 Dolinar, Brian S.,Berry, John F.. "Lewis acid enhanced axial ligation of [Mo2]4+ complexes". . p. 4658 - 4667. Retrieved 2013/05/22.
• 2、 Oda, Kazuaki,Fukuzawa, Yuichi,Ohno, Kosei,Machida, Minoru,Kanaoka, Yuichi. "PHOTOREACTION OF 1- AND 3-ARALKYL ALICYCLIC THIOIMIDES: FACILE SYNTHESES OF VARIOUS AZABICYCLOALKANES VIA NORRISH TYPE II PROCESS". . p. 71 - 78. Retrieved 2007/10/02.