1-phenyl-1,4-epoxy-1H,4H-naphtho<1,8-de><1,2>dioxepine

Base Information

• Chemical Name: 1-phenyl-1,4-epoxy-1H,4H-naphtho<1,8-de><1,2>dioxepine
• CAS No.: 127064-91-9
• Molecular Formula: C₁₈H₁₂O₃
• Molecular Weight: 276.291
• Mol file: 127064-91-9.mol

Synonyms:1-phenyl-1,4-epoxy-1H,4H-naphtho<1,8-de><1,2>dioxepine

Chemical Property of 1-phenyl-1,4-epoxy-1H,4H-naphtho<1,8-de><1,2>dioxepine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-phenyl-1,4-epoxy-1H,4H-naphtho<1,8-de><1,2>dioxepine

There total 14 articles about 1-phenyl-1,4-epoxy-1H,4H-naphtho<1,8-de><1,2>dioxepine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

methanol (67-56-1) + 1-phenylacenaphthylene (4044-56-8) → 1-phenyl-1-hydroperoxy-3-methoxy-1H,3H-naphtho<1.8-cd>pyran (127064-93-1) + 1-phenyl-1,4-epoxy-1H,4H-naphtho<1,8-de><1,2>dioxepine (127064-91-9)

Guidance literature:

With ozone; In dichloromethane; at -70 ℃; Product distribution; other solvent, temperature;

DOI:10.1021/jo00299a024

Reference yield: 54.0%

1-phenylacenaphthylene (4044-56-8) → 1-phenyl-1,4-epoxy-1H,4H-naphtho<1,8-de><1,2>dioxepine (127064-91-9)

Guidance literature:

With ozone; In tetrachloromethane;

Reference yield: 42.0%

8-benzoylnaphthalene-1-carbaldehyde (126614-37-7) → 1-phenyl-1,4-epoxy-1H,4H-naphtho<1,8-de><1,2>dioxepine (127064-91-9) + [8-(5-Heptyl-[1,2,4]trioxolan-3-yl)-naphthalen-1-yl]-phenyl-methanone

Guidance literature:

With n-C₇H₅CH=CHOMe; ozone; In dichloromethane; at -70 ℃;

upstream raw materials:

methanol

1-phenylacenaphthylene

1-acetyl-8-<(ethoxycarbonyl)vinyl>naphthalene

dioxirane

Refernces

• 1、 McCullough, Kevin J.,Sugimoto, Toshiya,Tanaka, Shogo,Kusabayashi, Shigekazu,Nojima, Masatomo. "Cycloaddition between Carbonyl Oxides and Dicarbonyl Compounds: Isolation and Characterization of Novel Polycyclic 1,2,4,6-Tetroxepane Derivatives". . p. 643 - 652. Retrieved 2007/10/02.
• 2、 Sugimoto, Toshiya,Nojima, Masatomo,Kusabayashi, Shigekazu,McCullough, Kevin J.. "[3 + 2 + 2] cycloaddition reactions between formaldehyde O-oxide and keto aldehydes: A new method for the synthesis of polycyclic peroxides". . p. 3690 - 3692. Retrieved 2007/10/02.