N-(2-Chloroethyl)dibenzylamine hydrochloride

Base Information Edit

Chemical Name:N-(2-Chloroethyl)dibenzylamine hydrochloride
CAS No.:55-43-6
Molecular Formula:C16H18 Cl N . Cl H
Molecular Weight:296.24
Hs Code.:2921499090
European Community (EC) Number:200-234-5
NSC Number:11491
UNII:W65S0F7870
DSSTox Substance ID:DTXSID3075337
Wikidata:Q27292380
ChEMBL ID:CHEMBL3272451
Mol file:55-43-6.mol

Synonyms:55-43-6;N-(2-Chloroethyl)dibenzylamine hydrochloride;Dibenamine hydrochloride;N,N-dibenzyl-2-chloroethanamine hydrochloride;Sympatholytin;Dibenzylchlorethamine hydrochloride;N,N-dibenzyl-2-chloroethanamine;hydrochloride;N,N-Dibenzyl-2-chloroethylamine hydrochloride;Dibenamine HCl;N-(2-CHLOROETHYL)DIBENZYLAMINE HCl;Dibenzylchlorethylamine hydrochloride;N,N-Dibenzylaminoethyl chloride hydrochloride;2-Chloroethyldibenzylamine hydrochloride;2-Dibenzylaminoethyl chloride hydrochloride;EINECS 200-234-5;NSC 11491;Dibenamine (hydrochloride);Benzenemethanamine, N-(2-chloroethyl)-N-(phenylmethyl)-, hydrochloride;Dibenzyl(2-chloroethyl)ammonium chloride;beta-Chloroethyldibenzylamine hydrochloride;DIBENZYLAMINE, N-(2-CHLOROETHYL)-, HYDROCHLORIDE;UNII-W65S0F7870;N,N-Dibenzyl-beta-chloroethylamine hydrochloride;NSC-11491;W65S0F7870;(2-Chloroethyl)dibenzylamine hydrochloride;N,N'-Dibenzyl-2-chloroethylamine hydrochloride;N,N-Dibenzyl-.beta.-chloroethylamine hydrochloride;MFCD00012518;N-(2-Chloroethyl)Dibenzylamine (Hydrochloride);N-(2-Chloroethyl)dibenzylamineHydrochloride;SCHEMBL334991;CHEMBL3272451;DTXSID3075337;WLN: G2N1R&1R &GH;NSC11491;DIBENAMINE HYDROCHLORIDE [MI];dibenzyl(2-chlorethyl)ammoniumchlorid;s5432;AKOS005267134;CCG-267427;DIBENAMINE HYDROCHLORIDE [WHO-DD];N-(chloroethy)dibenzylamine hydrochloride;AS-66599;dibenzyl(2-chloroethyl)amine hydrochloride;LS-61667;SY112039;dibenzyl-(2-chloroethyl)amine hydrochloride;HY-128380;.beta.-Chloroethyldibenzylamine hydrochloride;CS-0099460;FT-0631242;2-chloro-N,N-dibenzylethanamine hydrochloride;N-(2-Chloroethyl) dibenzylamine hydrochloride;N-(2-hloroethyl)ibenzylamine (Hydrochloride);D78410;A870196;2-(DIBENZYLAMINO)ETHYL CHLORIDE HYDROCHLORIDE;N-(2-Chloroethyl)dibenzylamine hydrochloride, 98%;(.BETA.-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE;(N,N-DIBENZYLAMINO)ETHYL CHLORIDE HYDROCHLORIDE;Q27292380

Suppliers and Price of N-(2-Chloroethyl)dibenzylamine hydrochloride

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Sympatholytin
5g
$ 195.00

TCI Chemical
N-(2-Chloroethyl)dibenzylamine Hydrochloride >98.0%(N)
500g
$ 1619.00

TCI Chemical
N-(2-Chloroethyl)dibenzylamine Hydrochloride >98.0%(N)
25g
$ 119.00

Sigma-Aldrich
N-(2-Chloroethyl)dibenzylamine hydrochloride 98%
5g
$ 86.40

Matrix Scientific
N,N-Dibenzyl-2-chloroethanamine hydrochloride
500mg
$ 199.00

Crysdot
N,N-Dibenzyl-2-chloroethanaminehydrochloride 95+%
500g
$ 1145.00

Crysdot
N,N-Dibenzyl-2-chloroethanaminehydrochloride 95+%
100g
$ 381.00

ChemScene
Dibenaminehydrochloride ≥98.0%
250mg
$ 50.00

Chem-Impex
N-(2-Chloroethyl)dibenzylamine hydrochloride
500G
$ 2034.91

Aronis compounds
N,N-dibenzyl-2-chloroethanaminehydrochloride
1g
$ 133.00

Total 22 raw suppliers

Chemical Property of N-(2-Chloroethyl)dibenzylamine hydrochloride Edit

Chemical Property:

Melting Point:190-193 °C(lit.)
Refractive Index:1.6300 (estimate)
Boiling Point:320°Cat760mmHg
Flash Point:147.3°C
PSA：3.24000
Density:1.107g/cm³
LogP:4.72960
Storage Temp.:Inert atmosphere,Room Temperature
Solubility.:almost transparency in Methanol
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:6
Exact Mass:295.0894550
Heavy Atom Count:19
Complexity:187

Purity/Quality:

98% ^*data from raw suppliers

Sympatholytin ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CN(CCCl)CC2=CC=CC=C2.Cl
Uses Sympatholytin was used as 5-Hydroxytryptamine antagonists in this study.Sympatholytin preferentially blocked postsynaptic alpha receptors.

Technology Process of N-(2-Chloroethyl)dibenzylamine hydrochloride

There total 3 articles about N-(2-Chloroethyl)dibenzylamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 101-06-4
N,N-dibenzyl-2-aminoethanol

: 55-43-6
N-(2-chloroethyl)dibenzylamine hydrochloride

Guidance literature:: With thionyl chloride; In dichloromethane; at -10 - 40 ℃; for 8h; Temperature; Large scale;

Reference yield:

: 100-39-0
benzyl bromide

: 55-43-6
N-(2-chloroethyl)dibenzylamine hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / acetonitrile / 8 h / -10 - 50 °C / Large scale

2: thionyl chloride / dichloromethane / 8 h / -10 - 40 °C / Large scale

With thionyl chloride; potassium carbonate; In dichloromethane; acetonitrile;