1-AMINO-3-METHYLBUTANE HYDROCHLORIDE

Base Information

• Chemical Name: 1-AMINO-3-METHYLBUTANE HYDROCHLORIDE
• CAS No.: 541-23-1
• Molecular Formula: C5H13 N . Cl H
• Molecular Weight: 123.62436
• Hs Code.: 2921199090
• Mol file: 541-23-1.mol

Synonyms:1-Butanamine,3-methyl-, hydrochloride (9CI); Isopentylamine, hydrochloride (8CI);3-Methyl-1-butanamine hydrochloride; Isoamylamine hydrochloride;Isopentylammonium chloride

Chemical Property of 1-AMINO-3-METHYLBUTANE HYDROCHLORIDE

Chemical Property:

• Melting Point: 65-69 °C
• Boiling Point: 92.7°Cat760mmHg
• Flash Point: 18.3°C
• PSA: 26.02000
• Density: 0.757g/cm³
• LogP: 2.49350
• Water Solubility.: Soluble in water
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 123.0814771
• Heavy Atom Count: 7
• Complexity: 25.1

Purity/Quality:

98%min ^*data from raw suppliers

Isopentylamine Hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)CC[NH3+].[Cl-]

Technology Process of 1-AMINO-3-METHYLBUTANE HYDROCHLORIDE

There total 11 articles about 1-AMINO-3-METHYLBUTANE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

Isovaleronitrile (625-28-5) → isoamylamine hydrochloride (541-23-1)

Guidance literature:

With hydrogenchloride; hydrogen; In propan-1-ol; water; at 60 - 70 ℃; for 18h; under 375.038 Torr; Flow reactor;

DOI:10.1002/open.201600166

Reference yield: 82.0%

1-nitro-3-methylbutane (627-67-8) → isoamylamine hydrochloride (541-23-1)

Guidance literature:

With ammonium formate; palladium on activated charcoal; In methanol; Ambient temperature;

DOI:10.1016/S0040-4039(01)91034-2

Reference yield: 74.0%

isobutylamide (541-46-8) → isoamylamine hydrochloride (541-23-1)

Guidance literature:

isobutylamide; With dodecacarbonyl-triangulo-triruthenium; 1,1,3,3-tetramethyldisilazane; In toluene; at 20 - 70 ℃; for 24.17h; Inert atmosphere;

With hydrogenchloride; In 1,4-dioxane; ethyl acetate; toluene; at 20 ℃; for 0.5h;

DOI:10.1002/adsc.201200835

upstream raw materials:

1-nitro-3-methylbutane

1-amino-3-methylbutane

sodium 4-styrenesulfonate

Benzhydrylidene-(3-methyl-butyl)-amine

Downstream raw materials:

(S)-t-butyl 1-(isopentylamino)-4-methyl-1-oxopentan-2-ylcarbamate

C₂₁H₃₆N₃O₅P

(S)-2-((N-(benzyloxycarbonyl)aminomethylphosphonyl)amino)-N-isopentyl-4-methylpentanamide lithium

4'-[[[2-[(3-methylbutyl)amino]-4-quinazolinyl]amino]methyl][1,1'-biphenyl]-2-carboxylic acid methyl ester

Refernces

• 1、 Neumann, Jacob,Bornschein, Christoph,Jiao, Haijun,Junge, Kathrin,Beller, Matthias. "Hydrogenation of Aliphatic and Aromatic Nitriles Using a Defined Ruthenium PNP Pincer Catalyst". supporting information. p. 5944 - 5948. Retrieved 2015/09/22.
• 2、 -. "METHOD FOR DECARBOXYLATION OF AMINO ACIDS VIA IMINE FORMATION". Page/Page column 0045; 0050; 0066; 0067. . Retrieved 2014/09/30.