1-Chloro-5-iodopentane

Base Information

• Chemical Name: 1-Chloro-5-iodopentane
• CAS No.: 60274-60-4
• Molecular Formula: C5H10 Cl I
• Molecular Weight: 232.492
• Hs Code.: 2903799090
• European Community (EC) Number: 262-137-4
• UNII: 9R3MCR55RT
• DSSTox Substance ID: DTXSID4069393
• Nikkaji Number: J298.811I
• Wikidata: Q81996261
• Mol file: 60274-60-4.mol

Synonyms:1-Chloro-5-iodopentane;60274-60-4;Pentane, 1-chloro-5-iodo-;Pentamethylene chloroiodide;1-iodo-5-chloropentane;EINECS 262-137-4;5-chloro-1-iodopentane;MFCD00039416;l-chloro-5-iodopentane;1-chloro-5-iodo-pentane;C5H10ClI;9R3MCR55RT;C5-H10-Cl-I;SCHEMBL1176613;1-Chloro-5-iodopentane, 97%;DTXSID4069393;AKOS015912745;AS-57644;1-Chloro-5-iodopentane stabilized over Cu;CS-0135342;FT-0607635;EN300-7359706;A869015;2-HYDROXY-4-CHLORO-5-SULFAMOYLBENZOIC ACID??

Chemical Property of 1-Chloro-5-iodopentane

Chemical Property:

• Vapor Pressure: 0.116mmHg at 25°C
• Refractive Index: 1.5305
• Boiling Point: 75-77°C 4mm
• Flash Point: 75-77°C/4mm
• PSA: 0.00000
• Density: 1.663
• LogP: 2.83050
• Storage Temp.: 2-8°C(protect from light)
• Sensitive.: Light Sensitive
• Water Solubility.: Not miscible or difficult to mix with water.
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 4
• Exact Mass: 231.95158
• Heavy Atom Count: 7
• Complexity: 31.3

Purity/Quality:

99% ^*data from raw suppliers

1-Chloro-5-iodopentane ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36-37

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CCCl)CCI
• Uses: 1-Chloro-5-iodopentane is used as a pharmaceutical intermediate.

Technology Process of 1-Chloro-5-iodopentane

There total 11 articles about 1-Chloro-5-iodopentane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,5-dichloropentane (628-76-2) → 1-chloro-5-iodopentane (60274-60-4)

Guidance literature:

With acetone; sodium iodide;

Reference yield:

1 ,5-pentanediol (111-29-5) → 1-chloro-5-iodopentane (60274-60-4)

Guidance literature:

Multi-step reaction with 2 steps

1: Py, SOCl₂

2: NaI / acetone

With pyridine; thionyl chloride; sodium iodide; In acetone;

DOI:10.1021/ja01484a030

Reference yield:

ethene (74-85-1) + Chloroiodomethane (593-71-5) → 1-chloro-5-iodopentane (60274-60-4)

Guidance literature:

With dibenzoyl peroxide;

DOI:10.1021/ja01161a095

upstream raw materials:

ethene

Chloroiodomethane

5-chloropentan-1-ol

1,5-dichloropentane

Downstream raw materials:

chloro-1 heptyne-6

(S)-5-Benzyl-2-(5-chloro-pentyl)-4-(4-methoxy-benzyl)-morpholin-3-one

1-chloro-5-(phenylselanyl)pentane

1-(5-chloro-pentyloxy)-4-(1,1-diallyl-but-3-enyl)-benzene

Refernces

• 1、 Mohan, Hari,Maity,Chattopadhyay,Mittal. "Transformation of OH-adduct of 1-chloro-4-iodobutane into intra-molecular radical cation in neutral aqueous solution". . p. 493 - 498. Retrieved 2007/10/03.