Technology Process of (Z)-tert-butyl (2-(4-bromo-2-formylstyryl)phenyl)carbamate
There total 6 articles about (Z)-tert-butyl (2-(4-bromo-2-formylstyryl)phenyl)carbamate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
sodium hydrogencarbonate; Dess-Martin periodane;
In
dichloromethane;
for 0.666667h;
Inert atmosphere;
DOI:10.1039/c4ob00694a
- Guidance literature:
-
Multi-step reaction with 4 steps
1: triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide / tetrahydrofuran / 16 h / Inert atmosphere; Schlenk technique
2: tetrahydrofuran / 48 h / 70 °C / Sealed tube
3: quinoline; 10 percent palladium on barium sulphate; hydrogen / methanol / 1.5 h
4: Dess-Martin periodane; sodium hydrogencarbonate / dichloromethane / 0.67 h / Inert atmosphere
With
quinoline; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; 10 percent palladium on barium sulphate; hydrogen; sodium hydrogencarbonate; Dess-Martin periodane; triethylamine;
In
tetrahydrofuran; methanol; dichloromethane;
1: |Sonogashira Cross-Coupling / 4: |Dess-Martin Oxidation;
DOI:10.1039/c4ob00694a
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: sulfuric acid; sodium nitrite / dimethyl sulfoxide / 1 h / 20 °C
1.2: 2 h
2.1: triethylamine; chloroformic acid ethyl ester / 1 h / 0 °C
2.2: 1.5 h
3.1: triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide / tetrahydrofuran / 16 h / Inert atmosphere; Schlenk technique
4.1: tetrahydrofuran / 48 h / 70 °C / Sealed tube
5.1: quinoline; 10 percent palladium on barium sulphate; hydrogen / methanol / 1.5 h
6.1: Dess-Martin periodane; sodium hydrogencarbonate / dichloromethane / 0.67 h / Inert atmosphere
With
quinoline; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; sulfuric acid; 10 percent palladium on barium sulphate; hydrogen; chloroformic acid ethyl ester; sodium hydrogencarbonate; Dess-Martin periodane; triethylamine; sodium nitrite;
In
tetrahydrofuran; methanol; dichloromethane; dimethyl sulfoxide;
3.1: |Sonogashira Cross-Coupling / 6.1: |Dess-Martin Oxidation;
DOI:10.1039/c4ob00694a