Ciprofloxacin Hydrochloride

Base Information Edit

Chemical Name:Ciprofloxacin Hydrochloride
CAS No.:93107-08-5
Molecular Formula:C17H18FN3O3^.HCl
Molecular Weight:367.808
Hs Code.:29339900
European Community (EC) Number:642-985-5,658-041-0,849-041-3
NSC Number:620634
UNII:0MP32MFP6C
DSSTox Substance ID:DTXSID1047788
Wikidata:Q27105154
NCI Thesaurus Code:C47976
RXCUI:81981
ChEMBL ID:CHEMBL1202
Mol file:93107-08-5.mol

Synonyms:Anhydrous, Ciprofloxacin Hydrochloride;Bay 09867;Bay-09867;Bay09867;Ciprinol;Cipro;Ciprofloxacin;Ciprofloxacin Hydrochloride;Ciprofloxacin Hydrochloride Anhydrous;Ciprofloxacin Monohydrochloride Monohydrate;Hydrochloride Anhydrous, Ciprofloxacin;Hydrochloride, Ciprofloxacin;Monohydrate, Ciprofloxacin Monohydrochloride;Monohydrochloride Monohydrate, Ciprofloxacin

Suppliers and Price of Ciprofloxacin Hydrochloride

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
Ciprofloxacin HCl Pharmaceutical Secondary Standard; Certified Reference Material
1 g
$ 80.10

Sigma-Aldrich
Ciprofloxacin hydrochloride European Pharmacopoeia (EP) Reference Standard
$ 190.00

Sigma-Aldrich
Ciprofloxacin hydrochloride United States Pharmacopeia (USP) Reference Standard
400 mg
$ 366.00

Crysdot
1-Cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylicacidhydrochloride 95+%
500g
$ 190.00

Crysdot
1-Cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylicacidhydrochloride 95+%
100g
$ 60.00

ChemScene
Ciprofloxacin(monohydrochloride) 99.73%
1g
$ 72.00

ChemScene
Ciprofloxacin(monohydrochloride) 99.73%
500mg
$ 50.00

ChemScene
Ciprofloxacin(monohydrochloride) 99.73%
5g
$ 108.00

Cayman Chemical
Ciprofloxacin (hydrochloride) ≥95%
50g
$ 125.00

Cayman Chemical
Ciprofloxacin (hydrochloride) ≥95%
10g
$ 48.00

Total 130 raw suppliers

Chemical Property of Ciprofloxacin Hydrochloride Edit

Chemical Property:

Appearance/Colour:white or light yellow crystalline powder
Melting Point:>300 °C
Boiling Point:581.8 °C at 760 mmHg
Flash Point:305.6 °C
PSA：74.57000
LogP:2.77910
Storage Temp.:Sealed in dry,Room Temperature
Solubility.:insoluble in EtOH; ≥33.87 mg/mL in H2O; ≥9.34 mg/mL in DMSO with ultrasonic
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:3
Exact Mass:367.1098973
Heavy Atom Count:25
Complexity:571

Purity/Quality:

99% ^*data from raw suppliers

Ciprofloxacin HCl Pharmaceutical Secondary Standard; Certified Reference Material ^*data from reagent suppliers

Safty Information:

Pictogram(s): R36/37/38:;
Hazard Codes: Xi:Irritant;
Statements: R36/37/38:;
Safety Statements: 24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC1N2C=C(C(=O)C3=CC(=C(C=C32)N4CCNCC4)F)C(=O)O.Cl
Recent ClinicalTrials:Bioequivalence Study of Ciprofloxacin in Healthy Adult Subjects Under Fasting Condition
Recent EU Clinical Trials:ABSORB 2:An exploratie study determining the oral antibiotic drug absorption in patients with short bowel syndrome.
Description Ciprofloxacin hydrochloride is the hydrochloride of ciprofloxacin, which is a synthetic second-generation quinolone antibacterial drug with broad-spectrum antibacterial activity and good bactericidal effect. It is 2 to 4 times stronger than enoxacin, and has antibacterial effects on Enterobacter, Pseudomonas aeruginosa, Haemophilus influenzae, Neisseria gonorrhoeae, Streptococcus, Legionella, and Staphylococcus aureus.
Uses Anti-bacterial Ciprofloxacin hydrochloride is a fluoroquinolone antibiotic that is widely used as an antimicrobial and immunomodulatory agent. Its range of activity includes most strains of bacterial pathogens capable of inducing respiratory, urinary tract, gastrointestinal, and abdominal infections. It functions by inhibiting DNA gyrase (a type II topoisomerase) and topoisomerase IV, the enzymes responsible for negative supercoiling of chromosomes and DNA strand separation, thus blocking initiation of bacterial replication. Most recently Ciprofloxacin hydrochloride has been used in the management of postexposure inhalational anthrax and radiation combined injury resulting from nuclear disasters.[Cayman Chemical]

Technology Process of Ciprofloxacin Hydrochloride

There total 26 articles about Ciprofloxacin Hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%