Norswertianolin

Base Information

• Chemical Name: Norswertianolin
• CAS No.: 54954-12-0
• Deprecated CAS: 26107-89-1,34472-02-1
• Molecular Formula: C19H18 O11
• Molecular Weight: 422.345
• UNII: 8FEU38L6GD
• ChEMBL ID: CHEMBL512072
• DSSTox Substance ID: DTXSID70203480
• Metabolomics Workbench ID: 50014
• Nikkaji Number: J788.371D
• Wikidata: Q27089366
• Mol file: 54954-12-0.mol

Synonyms:norswertianolin

Chemical Property of Norswertianolin

Chemical Property:

• Vapor Pressure: 1.79E-29mmHg at 25°C
• Boiling Point: 833.7°C at 760 mmHg
• Flash Point: 300.4°C
• PSA: 190.28000
• Density: 1.789g/cm³
• LogP: -0.75830
• XLogP3: 0.3
• Hydrogen Bond Donor Count: 7
• Hydrogen Bond Acceptor Count: 11
• Rotatable Bond Count: 3
• Exact Mass: 422.08491139
• Heavy Atom Count: 30
• Complexity: 632

Purity/Quality:

99%, ^*data from raw suppliers

NORSWERTIANOLIN 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C2C(=C1O)OC3=CC(=CC(=C3C2=O)O)O)OC4C(C(C(C(O4)CO)O)O)O
• Isomeric SMILES: C1=CC(=C2C(=C1O)OC3=CC(=CC(=C3C2=O)O)O)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O

Technology Process of Norswertianolin

There total 5 articles about Norswertianolin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,3,5,8-tetrahydroxyxanthone (2980-32-7) → bellidin 8-O-β-glucopyranoside (54954-12-0,26107-89-1)

Guidance literature:

Multi-step reaction with 4 steps

1: 67 percent / pyridine / 2 h / 100 °C

2: 96 percent / AlCl₃ / diethyl ether / 3 h / Heating

3: Ag₂CO₃, drierite / pyridine / 16 h

4: NaOMe / methanol / pH 10

With pyridine; calcium sulfate; aluminium trichloride; sodium methylate; silver carbonate; In pyridine; methanol; diethyl ether;

DOI:10.1002/hlca.19850680832

Reference yield:

5,8-dihydroxy-1,3-dimethoxy-9H-xanthen-9-one (103726-10-9) → bellidin 8-O-β-glucopyranoside (54954-12-0,26107-89-1)

Guidance literature:

Multi-step reaction with 5 steps

1: 85 percent / AlCl₃ / benzene / 4 h / Heating

2: 67 percent / pyridine / 2 h / 100 °C

3: 96 percent / AlCl₃ / diethyl ether / 3 h / Heating

4: Ag₂CO₃, drierite / pyridine / 16 h

5: NaOMe / methanol / pH 10

With pyridine; calcium sulfate; aluminium trichloride; sodium methylate; silver carbonate; In pyridine; methanol; diethyl ether; benzene;

DOI:10.1002/hlca.19850680832

Reference yield:

1,3,5-tribenzoyloxy-8-hydroxy-9H-xanthen-9-one (103726-21-2) → bellidin 8-O-β-glucopyranoside (54954-12-0,26107-89-1)

Guidance literature:

Multi-step reaction with 2 steps

1: Ag₂CO₃, drierite / pyridine / 16 h

2: NaOMe / methanol / pH 10

With calcium sulfate; sodium methylate; silver carbonate; In pyridine; methanol;

DOI:10.1002/hlca.19850680832

upstream raw materials:

1,3,5,8-tetrahydroxyxanthone

5,8-dihydroxy-1,3-dimethoxy-9H-xanthen-9-one

1,3,5-tribenzoyloxy-8-hydroxy-9H-xanthen-9-one

C₄₁H₂₄O₁₀

Downstream raw materials:

Acetic acid 6,8-diacetoxy-9-oxo-1-((2S,3R,4S,5R,6R)-3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yloxy)-9H-xanthen-4-yl ester

Refernces