Technology Process of 2-<3,4-di-(t-butyldimethylsilyloxy)-phenyl>-1,3-propylenedithioacetal
There total 2 articles about 2-<3,4-di-(t-butyldimethylsilyloxy)-phenyl>-1,3-propylenedithioacetal which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
1H-imidazole;
In
N,N-dimethyl-formamide;
Ambient temperature;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 88 percent / AcOH, BF3*Et2O / 5 °C
2: 95 percent / imidazole / dimethylformamide / Ambient temperature
With
1H-imidazole; boron trifluoride diethyl etherate; acetic acid;
In
N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) n-BuLi, i-Pr2NH / 1.) THF, -76 deg C, 0.5 h, 2.) THF, -76 deg C, 1 h
2: 48 percent / 1percent NaOH, Raney nickel W-2 / tetrahydrofuran / 5 h / Heating
3: 73 percent / 1.3M Et3N*HF / tetrahydrofuran / 2 h / Ambient temperature
With
sodium hydroxide; n-butyllithium; Raney nickel W-2; triethylamine hydrofluoride; diisopropylamine;
In
tetrahydrofuran;