1,2-Ethanediamine, N'-[2-(diethylamino)ethyl]-N,N-diethyl-

Base Information

• Chemical Name: 1,2-Ethanediamine, N'-[2-(diethylamino)ethyl]-N,N-diethyl-
• CAS No.: 123-12-6
• Molecular Formula: C12H29 N3
• Molecular Weight: 215.382
• Hs Code.: 2921290000
• European Community (EC) Number: 204-603-1
• NSC Number: 21238
• DSSTox Substance ID: DTXSID8059554
• Nikkaji Number: J27.942K
• Wikidata: Q81988857
• Mol file: 123-12-6.mol

Synonyms:123-12-6;N,N,N',N'-Tetraethyldiethylenetriamine;3,9-Diethyl-3,6,9-triazaundecane;1,2-Ethanediamine, N'-[2-(diethylamino)ethyl]-N,N-diethyl-;(2-{[2-(diethylamino)ethyl]amino}ethyl)diethylamine;C12H29N3;bis(2-diethylaminoethyl)amine;EINECS 204-603-1;MFCD00039880;NSC 21238;1,1,7,7-Tetraethyldiethylenetriamine;N-[2-(diethylamino)ethyl]-N',N'-diethylethane-1,2-diamine;1,2-Ethanediamine, N'-(2-(diethylamino)ethyl)-N,N-diethyl-;n1-(2-(diethylamino)ethyl)-n2,n2-diethylethane-1,2-diamine;1,2-Ethanediamine, N2-(2-(diethylamino)ethyl)-N1,N1-diethyl-;N,N,N inverted exclamation marka,N inverted exclamation marka-Tetraethyldiethylenetriamine;Diethylenetriamine, 1,1,7,7-tetraethyl-;NSC21238;N,N,N',N'-TETRAETHYL-DIETHYLENETRIAMINE;SCHEMBL229973;DTXSID8059554;NSC-21238;3,9-Triethyl-3,6,9-triazaundecane;AKOS000255698;Diethylenetriamine,1,7,7-tetraethyl-;WLN: 2N2&2N2&2N2&2;AS-81652;SY290798;CS-0260007;FT-0733086;1, N'-[2-(diethylamino)ethyl]-N,N-diethyl-;E78790;EN300-7440591;DIETHYLENETRIAMINE, N,N,N',N''-TETRAETHYL-;J-004890;N'-[2-(diethylamino)ethyl]-N,N-diethyl-1,2-ethanediamine;N,N,N',N'-Tetraethyldiethylenetriamine, technical grade, 90%;N-(2-(diethylamino)ethyl)-N',N' diethylethane-1,2-diamine;N,N,N inverted exclamation mark ,N inverted exclamation mark -Tetraethyldiethylenetriamine

Chemical Property of 1,2-Ethanediamine, N'-[2-(diethylamino)ethyl]-N,N-diethyl-

Chemical Property:

• Refractive Index: n20/D 1.448(lit.)
• Boiling Point: 262.6°Cat760mmHg
• PKA: 10.45±0.25(Predicted)
• Flash Point: 89.3°C
• PSA: 18.51000
• Density: 0.861g/cm³
• LogP: 1.65050
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 10
• Exact Mass: 215.236147938
• Heavy Atom Count: 15
• Complexity: 106

Purity/Quality:

98%,99%, ^*data from raw suppliers

N,N,N′,N′-Tetraethyldiethylenetriamine technical grade, 90% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCN(CC)CCNCCN(CC)CC
• Uses: N,N,N′,N′-Tetraethyldiethylenetriamine (TEDETA) has been used in the following studies:As N-substituted ethylenediamine ligand in the synthesis of [Ni(Et4dien)(NO2)2] (Et4dien=N,N,N′,N′-tetraethyldiethylenetriamine).As a reagent in the synthesis of adamantanyl connector, (2-(1-carbamoylmethyladamantane)di(ethyl(diethylmethylammonium))dichloride).As a reagent in the synthesis of aminated macroligand.As a reagent in the synthesis of precipiton ligand.As a multimodal ligand in the synthesis of P(S-DVB)-g-P(S-GMA)- TEDETA beads (poly(styrene-divinylbenzene)-graft-poly(styrene-glycidylmethacrylate)).

Technology Process of 1,2-Ethanediamine, N'-[2-(diethylamino)ethyl]-N,N-diethyl-

There total 9 articles about 1,2-Ethanediamine, N'-[2-(diethylamino)ethyl]-N,N-diethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.0%

2-chloro-N,N-diethylethylamine hydrochloride (869-24-9) + N,N-diethylethylenediamine (100-36-7) → N,N,N',N'-tetraethyldiethylenetriamine (123-12-6)

Guidance literature:

With sodium hydroxide; In water; at 65 - 70 ℃;

DOI:10.1007/s11172-018-2147-y

Reference yield:

diethylaminoacetonitrile (3010-02-4) → N,N,N',N'-tetraethyldiethylenetriamine (123-12-6) + ethylamine (75-04-7,85404-22-4) + diethylamine (109-89-7) + N,N-diethylethylenediamine (100-36-7)

Guidance literature:

Hydrogenation;

DOI:10.1021/ja01337a046

Reference yield:

diethylaminoacetonitrile (3010-02-4) → N,N,N',N'-tetraethyldiethylenetriamine (123-12-6)

Guidance literature:

With ethanol; nickel; Hydrogenation;

DOI:10.1021/ja01337a046

upstream raw materials:

bis-(2-chloroethyl)amine hydrochloride

diethylamine

2-(diethylamino)ethyl bromide

N,N-diethylethylenediamine

Downstream raw materials:

2,4-di-tert-butyl-6-bis(2-(diethylamino)ethyl)aminomethylphenol

C₂₆H₄₂N₄O

C₂₃H₄₃N₃O

N₁-(2-(diethylamino)ethyl)-N₂,N₂-diethyl-N₁-(6-o-tolylpyridin-2-yl)ethane-1,2-diamine

Refernces

• 1、 Hoang,Borisova, E. Ya.,Borisova, N. Yu.,Krylov,Lesnikov. "Synthesis of N 1,N 1,N 3,N 3-tetrasubstituted diethylenetriamines". . p. 840 - 843. Retrieved 2018/08/28.