Indane-5-sulfonamide

Base Information

• Chemical Name: Indane-5-sulfonamide
• CAS No.: 35203-93-1
• Molecular Formula: C9H11NO2S
• Molecular Weight: 197.258
• Hs Code.: 2935009090
• European Community (EC) Number: 252-432-6
• NSC Number: 91508
• UNII: XJL3C99615
• DSSTox Substance ID: DTXSID40188710
• Nikkaji Number: J289.932I
• Wikipedia: Indane-5-sulfonamide
• Wikidata: Q15303947
• Pharos Ligand ID: AA98RT9LU3Q9
• Metabolomics Workbench ID: 151313
• ChEMBL ID: CHEMBL364869
• Mol file: 35203-93-1.mol

Synonyms:indane-5-sulfonamide;2,3-dihydro-1H-indene-5-sulfonamide;35203-93-1;Indan-5-sulphonamide;5-Indansulfonamide;Indan-5-sulfonic acid amide;1H-Indene-5-sulfonamide, 2,3-dihydro-;CHEMBL364869;XJL3C99615;EINECS 252-432-6;NSC-91508;2qoa;2,3-dihydro-5-indenylsulfonamide;5-indanesulfonamide;NSC91508;indan-5-sulfonamide;D0LC0F;D0O1LJ;UNII-XJL3C99615;SCHEMBL2011443;DTXSID40188710;HMS3604H17;BDBM50155556;MFCD00021245;NSC 91508;AKOS000141119;AS-8808;DB08165;1h-indene-5-sulfonamide,2,3-dihydro-;CS-0159193;EN300-27000;Q15303947;Z45415660;MAJ

Chemical Property of Indane-5-sulfonamide

Chemical Property:

• Vapor Pressure: 6.58E-06mmHg at 25°C
• Refractive Index: 1.608
• Boiling Point: 377.8 °C at 760 mmHg
• PKA: 10.28±0.20(Predicted)
• Flash Point: 182.3 °C
• PSA: 68.54000
• Density: 1.337 g/cm³
• LogP: 2.60380
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 197.05104977
• Heavy Atom Count: 13
• Complexity: 281

Purity/Quality:

99% ^*data from raw suppliers

Indane-5-sulfonamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC2=C(C1)C=C(C=C2)S(=O)(=O)N

Technology Process of Indane-5-sulfonamide

There total 4 articles about Indane-5-sulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

indan-5-sulfonyl chloride (52205-85-3) + ammonia (7664-41-7) → 2,3-dihydro-5-indenylsulfonamide (35203-93-1)

Guidance literature:

In water; at 60 ℃;

Reference yield:

→ 2,3-dihydro-5-indenylsulfonamide (35203-93-1)

Guidance literature:

DOI:10.1021/ja01860a014 DOI:10.1021/ja01857a055

Reference yield:

indan-5-sulfonyl chloride (52205-85-3) → 2,3-dihydro-5-indenylsulfonamide (35203-93-1)

Guidance literature:

With ammonia; water;

upstream raw materials:

indan-5-sulfonyl chloride

ammonia

Downstream raw materials:

sulofenur

3-oxo-indan-5-sulfonamide

1-keto-5-indansulfonamide

C₂₁H₂₇N₄O₆PS₂

Refernces

• 1、 Breuer,Hohn. "Potential antidiabetic agents. I. Indan-, indole-, indoline-, coumaran- and dihydrothianaphthene sulfonylureas and sulfonylsemicarbazides". . p. 659 - 668. Retrieved 2007/10/08.